ID   Y2228_MYCMM             Reviewed;         306 AA.
AC   B2HP73;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Nucleotide-binding protein MMAR_2228 {ECO:0000255|HAMAP-Rule:MF_00636};
GN   OrderedLocusNames=MMAR_2228;
OS   Mycobacterium marinum (strain ATCC BAA-535 / M).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=216594;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-535 / M;
RX   PubMed=18403782; DOI=10.1101/gr.075069.107;
RA   Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA   Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA   Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA   Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA   Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA   Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT   "Insights from the complete genome sequence of Mycobacterium marinum on the
RT   evolution of Mycobacterium tuberculosis.";
RL   Genome Res. 18:729-741(2008).
CC   -!- FUNCTION: Displays ATPase and GTPase activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SIMILARITY: Belongs to the RapZ-like family. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
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DR   EMBL; CP000854; ACC40677.1; -; Genomic_DNA.
DR   RefSeq; WP_011739911.1; NC_010612.1.
DR   AlphaFoldDB; B2HP73; -.
DR   SMR; B2HP73; -.
DR   STRING; 216594.MMAR_2228; -.
DR   EnsemblBacteria; ACC40677; ACC40677; MMAR_2228.
DR   GeneID; 64260913; -.
DR   KEGG; mmi:MMAR_2228; -.
DR   eggNOG; COG1660; Bacteria.
DR   HOGENOM; CLU_059558_0_0_11; -.
DR   OMA; TVMSFGF; -.
DR   OrthoDB; 1603998at2; -.
DR   Proteomes; UP000001190; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00636; RapZ_like; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448; PTHR30448; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   PIRSF; PIRSF005052; P-loopkin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; GTP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..306
FT                   /note="Nucleotide-binding protein MMAR_2228"
FT                   /id="PRO_1000130768"
FT   BINDING         29..36
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
FT   BINDING         80..83
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
SQ   SEQUENCE   306 AA;  33204 MW;  72E3D268746E2AED CRC64;
     MTNHIAGGGN PPGPEGDASA GIDVVLVTGL SGAGRGTAAK VLEDLGWYVA DNLPPQLITR
     MVDFGLAAGS RITQLAVVMD VRSRGFTGDL DSVRNELATR NITPRVVFME ASDDMLVRRY
     EQNRRSHPLQ GGHTLAEGIA AERKMLEPVR ATADLIIDTS TLSVRGLREN IERAFGGDAA
     AITSVTVESF GFKYGLPMDA DMVMDVRFLP NPHWVDELRP LTGQHQAVSD YVLGRPGASE
     FLQTYHELLS LVVEGYRREG KRYMTVAIGC TGGKHRSVAI AEALVGLLRS NSRLSVRVLH
     RDLGRE