ID   Y222_TREPA              Reviewed;         148 AA.
AC   O83251;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Uncharacterized protein TP_0222;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0222;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65211.1; -; Genomic_DNA.
DR   PIR; C71353; C71353.
DR   RefSeq; WP_010881670.1; NC_021490.2.
DR   AlphaFoldDB; O83251; -.
DR   SMR; O83251; -.
DR   IntAct; O83251; 3.
DR   STRING; 243276.TPANIC_0222; -.
DR   EnsemblBacteria; AAC65211; AAC65211; TP_0222.
DR   GeneID; 57878760; -.
DR   KEGG; tpa:TP_0222; -.
DR   HOGENOM; CLU_1758026_0_0_12; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..148
FT                   /note="Uncharacterized protein TP_0222"
FT                   /id="PRO_0000014243"
FT   TRANSMEM        125..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          49..129
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   148 AA;  16224 MW;  389CE9EB3A5DA0BC CRC64;
     MWKRGVGALL WGMVLLRSFV AYADSQAATG GLLKEIMGEV ASIRLESNML KQQLRERHAE
     SAALKKALQT LDVKLEKAAK ALEESEHALS ESKELIETLR SELEILRQRV NALNMRLRRL
     EITNNVLIGV AVVCGVAAIG AGIYAAVK