ID   Y2235_MYCTO             Reviewed;         271 AA.
AC   P9WGA6; L0T907; P66883; Q10517;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Uncharacterized SURF1-like protein MT2294;
GN   OrderedLocusNames=MT2294;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SURF1 family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46578.1; -; Genomic_DNA.
DR   PIR; G70777; G70777.
DR   RefSeq; WP_003411514.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WGA6; -.
DR   EnsemblBacteria; AAK46578; AAK46578; MT2294.
DR   GeneID; 45426213; -.
DR   KEGG; mtc:MT2294; -.
DR   PATRIC; fig|83331.31.peg.2471; -.
DR   HOGENOM; CLU_047737_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd06662; SURF1; 1.
DR   InterPro; IPR002994; Surf1/Shy1.
DR   InterPro; IPR045214; Surf1/Surf4.
DR   PANTHER; PTHR23427; PTHR23427; 1.
DR   Pfam; PF02104; SURF1; 1.
DR   PROSITE; PS50895; SURF1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..271
FT                   /note="Uncharacterized SURF1-like protein MT2294"
FT                   /id="PRO_0000428395"
FT   TRANSMEM        11..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          245..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   271 AA;  29762 MW;  A875AC1CB7B7D161 CRC64;
     MPRLAFLLRP GWLALALVVV AFTYLCFTVL APWQLGKNAK TSRENQQIRY SLDTPPVPLK
     TLLPQQDSSA PDAQWRRVTA TGQYLPDVQV LARLRVVEGD QAFEVLAPFV VDGGPTVLVD
     RGYVRPQVGS HVPPIPRLPV QTVTITARLR DSEPSVAGKD PFVRDGFQQV YSINTGQVAA
     LTGVQLAGSY LQLIEDQPGG LGVLGVPHLD PGPFLSYGIQ WISFGILAPI GLGYFAYAEI
     RARRREKAGS PPPDKPMTVE QKLADRYGRR R