Y2237_DICDI
ID Y2237_DICDI Reviewed; 885 AA.
AC Q54ST3;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=DDT domain-containing protein DDB_G0282237;
GN ORFNames=DDB_G0282237;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00063,
CC ECO:0000255|PROSITE-ProRule:PRU00475}.
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DR EMBL; AAFI02000046; EAL66324.1; -; Genomic_DNA.
DR RefSeq; XP_640302.1; XM_635210.1.
DR AlphaFoldDB; Q54ST3; -.
DR STRING; 44689.DDB0216395; -.
DR PaxDb; Q54ST3; -.
DR EnsemblProtists; EAL66324; EAL66324; DDB_G0282237.
DR GeneID; 8623478; -.
DR KEGG; ddi:DDB_G0282237; -.
DR dictyBase; DDB_G0282237; -.
DR eggNOG; KOG1245; Eukaryota.
DR HOGENOM; CLU_012516_0_0_1; -.
DR InParanoid; Q54ST3; -.
DR OMA; RFTREIF; -.
DR PRO; PR:Q54ST3; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR SMART; SM00571; DDT; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome.
FT CHAIN 1..885
FT /note="DDT domain-containing protein DDB_G0282237"
FT /id="PRO_0000363984"
FT DOMAIN 20..125
FT /note="WAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00475"
FT DOMAIN 443..503
FT /note="DDT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00063"
FT REGION 141..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 217..260
FT /evidence="ECO:0000255"
FT COILED 530..565
FT /evidence="ECO:0000255"
FT COILED 593..628
FT /evidence="ECO:0000255"
FT COILED 674..782
FT /evidence="ECO:0000255"
FT COMPBIAS 151..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..264
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..602
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..632
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..727
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 104355 MW; 8505777055134BB8 CRC64;
MPLHGKDPFE LNKTRVKSGE EYFVIKFTKE HFKRYKDYID RYELYRQKIW TCSITGKQNL
TFEEALLSEK NASEKVSKVS ELLLPHCLEF IQYKEITLEE MTNQLYEFLL MNYYPGEIVS
FKKANVKYTG RIIELLENYN ESDEQSDNEQ QKKSSSSSST TTTTTTPTTP PTTTTTTSSS
INALSAIPIP KKEIKLQLYS DDENEEEDEK NNGDTSSDKK GEKEKEKEKE KEKEKEKEKE
KEKEKEKEKE KEKEKDSDTK SVRKYVDPRK KLDSIKKYYK IYVDSQGKNF IINIKDIQKR
EPPIFKPMVK DTIKTVAKKT KHLGGFWEVE PELIKKYNLE GLKIPSSVRK EVEQHLKRKR
IADGEILEDT EEESVDIESN DNSNSNGNSN SNNNLDSSDE SETERKRKRP KYPIEDQDVD
RENEETGKEN ERPIASSDFF CLSNTFGDFL MVWHFLNHFE KVLLLSPFPL DDFEMAIQHH
TETNILVESH IRLMKTIFTL PSYSSGTPKK TFGGKAITDR NWLATLRAYF QNEVKRIAIE
EKEKQEKLKQ LEEQNIRMLN LANELPGSDD EDDEMKLDED GNEIKKDVEM KDNDGTKDTK
KDDEENEEEE EEEEEEEEEV ASDEGEEEWK EENEIITSAD ANTICKVLKK KNYFKLSVEE
RIYILAYLVK QTIASEKIRK HLEKNVELGN EVKQEKKGII LEEKQLKQDD AAAAAEDDDE
NNEDDEEQQQ QEVKKPKGAK QKKPITPVVE KEIEKLEKKL EILDEKLEKY STRLESLGRD
RNYRNYWYWY QLPSKIYVEN ENGGWEYYSS KKELDDLIKY LDNRGIRERK LLFNIKPKYD
FIVSQLEKKN KEIIEQIQFE SKRSQRIKQL YTEKSYISWE NKYDY
