ID   Y223_HAEIN              Reviewed;         300 AA.
AC   P44579;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-1998, sequence version 3.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Uncharacterized transporter HI_0223;
GN   OrderedLocusNames=HI_0223;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   SEQUENCE REVISION.
RA   White O., Clayton R.A., Kerlavage A.R., Fleischmann R.D., Peterson J.,
RA   Hickey E., Dodson R., Gwinn M.;
RL   Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; L42023; AAC21892.1; -; Genomic_DNA.
DR   RefSeq; NP_438395.1; NC_000907.1.
DR   AlphaFoldDB; P44579; -.
DR   SMR; P44579; -.
DR   STRING; 71421.HI_0223; -.
DR   EnsemblBacteria; AAC21892; AAC21892; HI_0223.
DR   KEGG; hin:HI_0223; -.
DR   PATRIC; fig|71421.8.peg.236; -.
DR   eggNOG; COG2962; Bacteria.
DR   HOGENOM; CLU_054508_2_0_6; -.
DR   OMA; FWLFMWA; -.
DR   PhylomeDB; P44579; -.
DR   BioCyc; HINF71421:G1GJ1-240-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR000620; EamA_dom.
DR   InterPro; IPR004626; RarD.
DR   PANTHER; PTHR22911:SF114; PTHR22911:SF114; 1.
DR   Pfam; PF00892; EamA; 1.
DR   TIGRFAMs; TIGR00688; rarD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..300
FT                   /note="Uncharacterized transporter HI_0223"
FT                   /id="PRO_0000108157"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        243..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   300 AA;  34181 MW;  695BC144469089B7 CRC64;
     MKFKMKVVTQ GILLCIFSQC LFGILYLFSI WLQPLSGTDV FAWRMLTMIF GLLLILFPTI
     GCRSLLSLIT TTLGKSWTRW VLFLLGTLDA GSQFWLFMWA PLNGEGINIA MGYFLFPLIM
     AVLGWAWLKE RLSFIQKIAL LLAAAGVAHE LWHTQSFSWT SLWVCTVYPF YYLSRKWMKI
     PALQGITLDI ILISIPCFIY ILSQSDTLSL VTQEYRYWLL LPALGIVSAI SLSANLKSSQ
     QIPVSIFAVL SYIEPILLFL IAVFVLDNQI TTSDYFTYVP IWLSLIVIGI EGLLNKKKVR