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Y2245_ARATH
ID   Y2245_ARATH             Reviewed;         802 AA.
AC   Q8S8L9;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=Uncharacterized TPR repeat-containing protein At2g32450;
GN   OrderedLocusNames=At2g32450; ORFNames=T32F6.3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=cv. Columbia;
RX   PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA   Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA   Rathjen J.P., Peck S.C.;
RT   "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT   thaliana.";
RL   J. Proteomics 72:439-451(2009).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19376835; DOI=10.1104/pp.109.138677;
RA   Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA   Grossmann J., Gruissem W., Baginsky S.;
RT   "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT   chloroplast kinase substrates and phosphorylation networks.";
RL   Plant Physiol. 150:889-903(2009).
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DR   EMBL; AC005700; AAM15073.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC08687.1; -; Genomic_DNA.
DR   EMBL; BT004231; AAO42246.1; -; mRNA.
DR   EMBL; BT005684; AAO64104.1; -; mRNA.
DR   PIR; C84733; C84733.
DR   PIR; T02544; T02544.
DR   RefSeq; NP_180804.1; NM_128804.3.
DR   AlphaFoldDB; Q8S8L9; -.
DR   SMR; Q8S8L9; -.
DR   BioGRID; 3153; 2.
DR   IntAct; Q8S8L9; 1.
DR   STRING; 3702.AT2G32450.1; -.
DR   iPTMnet; Q8S8L9; -.
DR   PaxDb; Q8S8L9; -.
DR   PRIDE; Q8S8L9; -.
DR   ProteomicsDB; 242538; -.
DR   EnsemblPlants; AT2G32450.1; AT2G32450.1; AT2G32450.
DR   GeneID; 817806; -.
DR   Gramene; AT2G32450.1; AT2G32450.1; AT2G32450.
DR   KEGG; ath:AT2G32450; -.
DR   Araport; AT2G32450; -.
DR   TAIR; locus:2060206; AT2G32450.
DR   eggNOG; KOG1124; Eukaryota.
DR   HOGENOM; CLU_019072_0_0_1; -.
DR   InParanoid; Q8S8L9; -.
DR   OMA; NQFLEMY; -.
DR   OrthoDB; 228087at2759; -.
DR   PhylomeDB; Q8S8L9; -.
DR   PRO; PR:Q8S8L9; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8S8L9; baseline and differential.
DR   Genevisible; Q8S8L9; AT.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR   GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   Gene3D; 1.25.40.10; -; 3.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   SMART; SM00028; TPR; 7.
DR   SUPFAM; SSF47473; SSF47473; 2.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50005; TPR; 7.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   1: Evidence at protein level;
KW   Calcium; Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..802
FT                   /note="Uncharacterized TPR repeat-containing protein
FT                   At2g32450"
FT                   /id="PRO_0000311117"
FT   DOMAIN          6..41
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   REPEAT          229..262
FT                   /note="TPR 1"
FT   REPEAT          264..296
FT                   /note="TPR 2"
FT   REPEAT          305..338
FT                   /note="TPR 3"
FT   REPEAT          339..372
FT                   /note="TPR 4"
FT   REPEAT          373..406
FT                   /note="TPR 5"
FT   REPEAT          407..440
FT                   /note="TPR 6"
FT   REPEAT          442..474
FT                   /note="TPR 7"
FT   DOMAIN          595..630
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
SQ   SEQUENCE   802 AA;  90229 MW;  0DE301F6D2DE1783 CRC64;
     MTTRGSRSEK VKRIFQQFDG NLDGGLSREE MSALVVAVNP RVKFSDEQIS AILDEVFRTY
     AEFIDGDKGL TFDGLLRTYD DGAGDVDRDF DALGIEFNEE TKGASEASSS SITDERAVEA
     QKQQRTAAWA VSPNHGIVFD ETWKLVDDLE ILVKRLKSKQ EKDGKLKVDN NNVDAFSEAG
     WSRELGPSSD ISDKRIYWEE SSHDYGVFVK ELGVLRSKAD GARSREEAFD GHMAIGKVLY
     EHQLFKEALV SFKRACELQP TDVRPHFKAG NCLYVLGKYK ESKDEFLLAL EAAESGGNQW
     AYLLPQIYVN LGISLEGEGM VLSACEYYRE AAILCPTHYR ALKLLGSALF GVGEYRAAVK
     ALEEAIYLKP DYADAHCDLA SSLHAMGEDE RAIEVFQRAI DLKPGHVDAL YNLGGLYMDL
     GRFQRASEMY TRVLAVWPNH WRAQLNKAVS LLGAGETEEA KRALKEALKM TNRVELHDAV
     SHLKQLQKKK KVKKGNSANE EGPFIVVESS KFKTVGEKTT LRPDLAIALQ VRAFQRVTRL
     WKCDVEALRR EMRDNNVPVS YSGNGIPTKS IRRPNLEEIL RRLLNVLKPE TFQGAIKAIN
     EKILSVLDDS GSGRVDLGMF YAVIAPLCGG HPDKRKRVAF DALLWKPVNE GSSQITKMEA
     VKYIKLLRAI YIPSQGMSEM LEVHGESDDT STVTFNQFLE MYDDSEWGFG IMSTVFKLET
     RDRNRHGNQV CSVCRYPIIG SRFKEVKTGF SLCNQCYSEG KIPPTFKQQE EYKFREYASE
     VEAMKAKCVC FSMQSHKKTI AT
 
 
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