Y2245_ARATH
ID Y2245_ARATH Reviewed; 802 AA.
AC Q8S8L9;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=Uncharacterized TPR repeat-containing protein At2g32450;
GN OrderedLocusNames=At2g32450; ORFNames=T32F6.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Columbia;
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
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DR EMBL; AC005700; AAM15073.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08687.1; -; Genomic_DNA.
DR EMBL; BT004231; AAO42246.1; -; mRNA.
DR EMBL; BT005684; AAO64104.1; -; mRNA.
DR PIR; C84733; C84733.
DR PIR; T02544; T02544.
DR RefSeq; NP_180804.1; NM_128804.3.
DR AlphaFoldDB; Q8S8L9; -.
DR SMR; Q8S8L9; -.
DR BioGRID; 3153; 2.
DR IntAct; Q8S8L9; 1.
DR STRING; 3702.AT2G32450.1; -.
DR iPTMnet; Q8S8L9; -.
DR PaxDb; Q8S8L9; -.
DR PRIDE; Q8S8L9; -.
DR ProteomicsDB; 242538; -.
DR EnsemblPlants; AT2G32450.1; AT2G32450.1; AT2G32450.
DR GeneID; 817806; -.
DR Gramene; AT2G32450.1; AT2G32450.1; AT2G32450.
DR KEGG; ath:AT2G32450; -.
DR Araport; AT2G32450; -.
DR TAIR; locus:2060206; AT2G32450.
DR eggNOG; KOG1124; Eukaryota.
DR HOGENOM; CLU_019072_0_0_1; -.
DR InParanoid; Q8S8L9; -.
DR OMA; NQFLEMY; -.
DR OrthoDB; 228087at2759; -.
DR PhylomeDB; Q8S8L9; -.
DR PRO; PR:Q8S8L9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8S8L9; baseline and differential.
DR Genevisible; Q8S8L9; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF47473; SSF47473; 2.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS50005; TPR; 7.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 1: Evidence at protein level;
KW Calcium; Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..802
FT /note="Uncharacterized TPR repeat-containing protein
FT At2g32450"
FT /id="PRO_0000311117"
FT DOMAIN 6..41
FT /note="EF-hand 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT REPEAT 229..262
FT /note="TPR 1"
FT REPEAT 264..296
FT /note="TPR 2"
FT REPEAT 305..338
FT /note="TPR 3"
FT REPEAT 339..372
FT /note="TPR 4"
FT REPEAT 373..406
FT /note="TPR 5"
FT REPEAT 407..440
FT /note="TPR 6"
FT REPEAT 442..474
FT /note="TPR 7"
FT DOMAIN 595..630
FT /note="EF-hand 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
SQ SEQUENCE 802 AA; 90229 MW; 0DE301F6D2DE1783 CRC64;
MTTRGSRSEK VKRIFQQFDG NLDGGLSREE MSALVVAVNP RVKFSDEQIS AILDEVFRTY
AEFIDGDKGL TFDGLLRTYD DGAGDVDRDF DALGIEFNEE TKGASEASSS SITDERAVEA
QKQQRTAAWA VSPNHGIVFD ETWKLVDDLE ILVKRLKSKQ EKDGKLKVDN NNVDAFSEAG
WSRELGPSSD ISDKRIYWEE SSHDYGVFVK ELGVLRSKAD GARSREEAFD GHMAIGKVLY
EHQLFKEALV SFKRACELQP TDVRPHFKAG NCLYVLGKYK ESKDEFLLAL EAAESGGNQW
AYLLPQIYVN LGISLEGEGM VLSACEYYRE AAILCPTHYR ALKLLGSALF GVGEYRAAVK
ALEEAIYLKP DYADAHCDLA SSLHAMGEDE RAIEVFQRAI DLKPGHVDAL YNLGGLYMDL
GRFQRASEMY TRVLAVWPNH WRAQLNKAVS LLGAGETEEA KRALKEALKM TNRVELHDAV
SHLKQLQKKK KVKKGNSANE EGPFIVVESS KFKTVGEKTT LRPDLAIALQ VRAFQRVTRL
WKCDVEALRR EMRDNNVPVS YSGNGIPTKS IRRPNLEEIL RRLLNVLKPE TFQGAIKAIN
EKILSVLDDS GSGRVDLGMF YAVIAPLCGG HPDKRKRVAF DALLWKPVNE GSSQITKMEA
VKYIKLLRAI YIPSQGMSEM LEVHGESDDT STVTFNQFLE MYDDSEWGFG IMSTVFKLET
RDRNRHGNQV CSVCRYPIIG SRFKEVKTGF SLCNQCYSEG KIPPTFKQQE EYKFREYASE
VEAMKAKCVC FSMQSHKKTI AT