ID   Y2248_DICDI             Reviewed;         314 AA.
AC   Q54DH5;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Uncharacterized protein DDB_G0292248;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0292248;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=12796308; DOI=10.1128/ec.2.3.627-637.2003;
RA   Maeda M., Sakamoto H., Iranfar N., Fuller D., Maruo T., Ogihara S.,
RA   Morio T., Urushihara H., Tanaka Y., Loomis W.F.;
RT   "Changing patterns of gene expression in Dictyostelium prestalk cell
RT   subtypes recognized by in situ hybridization with genes from microarray
RT   analyses.";
RL   Eukaryot. Cell 2:627-637(2003).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=15470642; DOI=10.1387/ijdb.041862ns;
RA   Shimada N., Maeda M., Urushihara H., Kawata T.;
RT   "Identification of new modes of Dd-STATa regulation of gene expression in
RT   Dictyostelium by in situ hybridisation.";
RL   Int. J. Dev. Biol. 48:679-682(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in prestalk pstA and pstO cells in the
CC       slug stage. Preferentially restricted to pstO cells during culmination.
CC       {ECO:0000269|PubMed:12796308}.
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DR   EMBL; AAFI02000188; EAL61334.1; -; Genomic_DNA.
DR   RefSeq; XP_629752.1; XM_629750.1.
DR   AlphaFoldDB; Q54DH5; -.
DR   STRING; 44689.DDB0229935; -.
DR   PaxDb; Q54DH5; -.
DR   EnsemblProtists; EAL61334; EAL61334; DDB_G0292248.
DR   GeneID; 8628581; -.
DR   KEGG; ddi:DDB_G0292248; -.
DR   dictyBase; DDB_G0292248; -.
DR   eggNOG; ENOG502RHFE; Eukaryota.
DR   HOGENOM; CLU_077028_0_0_1; -.
DR   InParanoid; Q54DH5; -.
DR   OMA; HREHETP; -.
DR   PhylomeDB; Q54DH5; -.
DR   PRO; PR:Q54DH5; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR040310; DDB_G0292248-like.
DR   PANTHER; PTHR31648; PTHR31648; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..314
FT                   /note="Uncharacterized protein DDB_G0292248"
FT                   /id="PRO_0000392665"
FT   REGION          252..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..266
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..282
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        283..304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        43
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        96
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        109
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        116
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        117
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        161
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   314 AA;  36263 MW;  9B94673F59882961 CRC64;
     MKVSLLIFLI ILVGVIKSFD INSIDDSHWE SDEGFEHHKC WKNLTGYYTE FALSAYNTMF
     PTPYGVIPVS FYEGGVVTAD IKGQQMYVHY GIVAKNFTTW GQYYAYGKNQ TQYVVNNSSC
     VAMKLQFPFP DKLPKFKKVG TTKIGQTDVD VWIVKGKQQC NVTRSCILIQ KDTCTLMSAN
     FGNKDKSNLG FSLLNYYRYE NKPHYDKFQL PSQCWDVKPK DENENKEEQG LFANEEELEN
     KEYFGDNQQA PSMRITKNNP HLNNNNNNKK YHHREHETPN PDLIKTTTKT STKTTSFSRA
     TNDSPKSIDF HHLF