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Y2248_HALVD
ID   Y2248_HALVD             Reviewed;         271 AA.
AC   D4GVW4; A0A1U8QXI0; A0A384LIQ8; L9VAT0;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2016, sequence version 2.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Uncharacterized motility-related protein HVO_2248 {ECO:0000305};
GN   OrderedLocusNames=HVO_2248 {ECO:0000312|EMBL:ADE02430.2};
GN   ORFNames=C498_06513 {ECO:0000312|EMBL:ELY33473.1};
OS   Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS   NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=309800 {ECO:0000312|EMBL:ADE02430.2};
RN   [1] {ECO:0000312|EMBL:ADE02430.2, ECO:0000312|Proteomes:UP000008243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC   B-1768 / DS2 {ECO:0000312|Proteomes:UP000008243};
RX   PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA   Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA   Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA   Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT   "The complete genome sequence of Haloferax volcanii DS2, a model
RT   archaeon.";
RL   PLoS ONE 5:E9605-E9605(2010).
RN   [2] {ECO:0000312|EMBL:ELY33473.1, ECO:0000312|Proteomes:UP000011532}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC   B-1768 / DS2 {ECO:0000312|Proteomes:UP000011532};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
RN   [3]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=DS2 / DS70 {ECO:0000303|PubMed:33396553};
RX   PubMed=33396553; DOI=10.3390/genes12010058;
RA   Collins M., Afolayan S., Igiraneza A.B., Schiller H., Krespan E.,
RA   Beiting D.P., Dyall-Smith M., Pfeiffer F., Pohlschroder M.;
RT   "Mutations Affecting HVO_1357 or HVO_2248 Cause Hypermotility in Haloferax
RT   volcanii, Suggesting Roles in Motility Regulation.";
RL   Genes (Basel) 12:0-0(2020).
CC   -!- FUNCTION: May be involved in swimming motility.
CC       {ECO:0000305|PubMed:33396553}.
CC   -!- DISRUPTION PHENOTYPE: Cells having transposon insertions in this gene
CC       are hypermotile. {ECO:0000269|PubMed:33396553}.
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DR   EMBL; CP001956; ADE02430.2; -; Genomic_DNA.
DR   EMBL; AOHU01000041; ELY33473.1; -; Genomic_DNA.
DR   RefSeq; WP_004042136.1; NZ_AOHU01000041.1.
DR   STRING; 309800.C498_06513; -.
DR   EnsemblBacteria; ADE02430; ADE02430; HVO_2248.
DR   EnsemblBacteria; ELY33473; ELY33473; C498_06513.
DR   GeneID; 8926697; -.
DR   KEGG; hvo:HVO_2248; -.
DR   PATRIC; fig|309800.29.peg.1274; -.
DR   eggNOG; arCOG10164; Archaea.
DR   OrthoDB; 55803at2157; -.
DR   Proteomes; UP000008243; Chromosome.
DR   Proteomes; UP000011532; Unassembled WGS sequence.
DR   GO; GO:0071975; P:cell swimming; IMP:UniProtKB.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..271
FT                   /note="Uncharacterized motility-related protein HVO_2248"
FT                   /id="PRO_0000454794"
FT   REGION          233..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   271 AA;  31361 MW;  956E9CE5C1EA2689 CRC64;
     MSEQRVTFNG DTRVLYRQAV RTPLPNEDAE RLFHENMMNI ADAQERKADM LADPDISLLE
     AYETQLEGIA KSYKRRCRHI AGDDYEEIAM AYNRGARDDR VGALTAYYFE GLWRMQQRIT
     VTDMLFFPII LRYPDCFTVN IRFASGHTTT ESVLYESPEH STEELDDEYA ERYYNESLYS
     QKEAAEYIRD TAEIIREEFP SPDESTFEER QYGGITSAGG RKGPVFSSML KRVEPDPNRF
     SEPVDQPTLV EEGKEARRTE RELLPEGAIV L
 
 
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