Y2248_HALVD
ID Y2248_HALVD Reviewed; 271 AA.
AC D4GVW4; A0A1U8QXI0; A0A384LIQ8; L9VAT0;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 30-NOV-2016, sequence version 2.
DT 03-AUG-2022, entry version 43.
DE RecName: Full=Uncharacterized motility-related protein HVO_2248 {ECO:0000305};
GN OrderedLocusNames=HVO_2248 {ECO:0000312|EMBL:ADE02430.2};
GN ORFNames=C498_06513 {ECO:0000312|EMBL:ELY33473.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000312|EMBL:ADE02430.2};
RN [1] {ECO:0000312|EMBL:ADE02430.2, ECO:0000312|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC B-1768 / DS2 {ECO:0000312|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
RN [2] {ECO:0000312|EMBL:ELY33473.1, ECO:0000312|Proteomes:UP000011532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC B-1768 / DS2 {ECO:0000312|Proteomes:UP000011532};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [3]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=DS2 / DS70 {ECO:0000303|PubMed:33396553};
RX PubMed=33396553; DOI=10.3390/genes12010058;
RA Collins M., Afolayan S., Igiraneza A.B., Schiller H., Krespan E.,
RA Beiting D.P., Dyall-Smith M., Pfeiffer F., Pohlschroder M.;
RT "Mutations Affecting HVO_1357 or HVO_2248 Cause Hypermotility in Haloferax
RT volcanii, Suggesting Roles in Motility Regulation.";
RL Genes (Basel) 12:0-0(2020).
CC -!- FUNCTION: May be involved in swimming motility.
CC {ECO:0000305|PubMed:33396553}.
CC -!- DISRUPTION PHENOTYPE: Cells having transposon insertions in this gene
CC are hypermotile. {ECO:0000269|PubMed:33396553}.
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DR EMBL; CP001956; ADE02430.2; -; Genomic_DNA.
DR EMBL; AOHU01000041; ELY33473.1; -; Genomic_DNA.
DR RefSeq; WP_004042136.1; NZ_AOHU01000041.1.
DR STRING; 309800.C498_06513; -.
DR EnsemblBacteria; ADE02430; ADE02430; HVO_2248.
DR EnsemblBacteria; ELY33473; ELY33473; C498_06513.
DR GeneID; 8926697; -.
DR KEGG; hvo:HVO_2248; -.
DR PATRIC; fig|309800.29.peg.1274; -.
DR eggNOG; arCOG10164; Archaea.
DR OrthoDB; 55803at2157; -.
DR Proteomes; UP000008243; Chromosome.
DR Proteomes; UP000011532; Unassembled WGS sequence.
DR GO; GO:0071975; P:cell swimming; IMP:UniProtKB.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..271
FT /note="Uncharacterized motility-related protein HVO_2248"
FT /id="PRO_0000454794"
FT REGION 233..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 271 AA; 31361 MW; 956E9CE5C1EA2689 CRC64;
MSEQRVTFNG DTRVLYRQAV RTPLPNEDAE RLFHENMMNI ADAQERKADM LADPDISLLE
AYETQLEGIA KSYKRRCRHI AGDDYEEIAM AYNRGARDDR VGALTAYYFE GLWRMQQRIT
VTDMLFFPII LRYPDCFTVN IRFASGHTTT ESVLYESPEH STEELDDEYA ERYYNESLYS
QKEAAEYIRD TAEIIREEFP SPDESTFEER QYGGITSAGG RKGPVFSSML KRVEPDPNRF
SEPVDQPTLV EEGKEARRTE RELLPEGAIV L