ID   Y224_METKA              Reviewed;         378 AA.
AC   Q8TYR8;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=UPF0284 protein MK0224 {ECO:0000255|HAMAP-Rule:MF_01086};
GN   OrderedLocusNames=MK0224;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- SIMILARITY: Belongs to the UPF0284 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01086}.
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DR   EMBL; AE009439; AAM01441.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TYR8; -.
DR   SMR; Q8TYR8; -.
DR   STRING; 190192.MK0224; -.
DR   EnsemblBacteria; AAM01441; AAM01441; MK0224.
DR   KEGG; mka:MK0224; -.
DR   PATRIC; fig|190192.8.peg.225; -.
DR   HOGENOM; CLU_053134_0_0_2; -.
DR   OMA; TRWVAED; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0008939; F:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity; IEA:InterPro.
DR   CDD; cd02439; DMB-PRT_CobT; 1.
DR   Gene3D; 3.40.50.10210; -; 1.
DR   HAMAP; MF_01086; UPF0284; 1.
DR   InterPro; IPR003200; Nict_dMeBzImd_PRibTrfase.
DR   InterPro; IPR002805; Nict_dMeBzImd_PRibTrfase_arc.
DR   InterPro; IPR036087; Nict_dMeBzImd_PRibTrfase_sf.
DR   PANTHER; PTHR38811; PTHR38811; 1.
DR   Pfam; PF02277; DBI_PRT; 1.
DR   SUPFAM; SSF52733; SSF52733; 1.
DR   TIGRFAMs; TIGR00303; TIGR00303; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..378
FT                   /note="UPF0284 protein MK0224"
FT                   /id="PRO_0000151052"
SQ   SEQUENCE   378 AA;  40330 MW;  26C0EB10DBCF6ADB CRC64;
     MPNANQASAG VGALKEVLPG IRALGDLEAA EKVVKRCSGG STVMVCVIGS TEISRVPGIS
     AAGKTPESTF HTPAGDVELI YYDRIINAEE VPQNPVGAPS PAVITKAVVN LASIPFLTVD
     AGAAVKPACP YIDLGGEVAR DFREGPALSE ETYDRLLEFG KTLGKELTRD VDFLTVGESV
     PGGTTTAMAV MTALGYETSE KFASSSHDSP HDIKERVVKE GLEAQGVEPG DLDAHEAIRR
     FGDPMMPAVV GIIYGSRTPV LLAGGTQMAP ILAYLAEEGQ LDPERVFVGT TKYVVEDEDS
     DIESLFRQVG DYVLFSADPG FSESKFRGFR LYEEGYVKEG VGAGGAQVAA ALKTKGEITP
     KDVLRECERV YERWMDKF