ID   Y2259_MYCBO             Reviewed;         271 AA.
AC   P66884; A0A1R3Y0M1; Q10517; X2BK64;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Uncharacterized SURF1-like protein Mb2259;
GN   OrderedLocusNames=BQ2027_MB2259;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SURF1 family. {ECO:0000305}.
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DR   EMBL; LT708304; SIU00869.1; -; Genomic_DNA.
DR   RefSeq; NP_855908.1; NC_002945.3.
DR   RefSeq; WP_003411514.1; NC_002945.4.
DR   AlphaFoldDB; P66884; -.
DR   EnsemblBacteria; SIU00869; SIU00869; BQ2027_MB2259.
DR   GeneID; 45426213; -.
DR   PATRIC; fig|233413.5.peg.2479; -.
DR   OMA; MAYAVQW; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd06662; SURF1; 1.
DR   InterPro; IPR002994; Surf1/Shy1.
DR   InterPro; IPR045214; Surf1/Surf4.
DR   PANTHER; PTHR23427; PTHR23427; 1.
DR   Pfam; PF02104; SURF1; 1.
DR   PROSITE; PS50895; SURF1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..271
FT                   /note="Uncharacterized SURF1-like protein Mb2259"
FT                   /id="PRO_0000215663"
FT   TRANSMEM        11..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          245..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   271 AA;  29762 MW;  A875AC1CB7B7D161 CRC64;
     MPRLAFLLRP GWLALALVVV AFTYLCFTVL APWQLGKNAK TSRENQQIRY SLDTPPVPLK
     TLLPQQDSSA PDAQWRRVTA TGQYLPDVQV LARLRVVEGD QAFEVLAPFV VDGGPTVLVD
     RGYVRPQVGS HVPPIPRLPV QTVTITARLR DSEPSVAGKD PFVRDGFQQV YSINTGQVAA
     LTGVQLAGSY LQLIEDQPGG LGVLGVPHLD PGPFLSYGIQ WISFGILAPI GLGYFAYAEI
     RARRREKAGS PPPDKPMTVE QKLADRYGRR R