ID   Y225_MYCGE              Reviewed;         489 AA.
AC   P47467; Q49208;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Uncharacterized protein MG225;
GN   OrderedLocusNames=MG225;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 225-286.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.genitalium MG226. {ECO:0000305}.
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DR   EMBL; L43967; AAC71446.1; -; Genomic_DNA.
DR   EMBL; U01756; AAD10570.1; -; Genomic_DNA.
DR   PIR; H64224; H64224.
DR   RefSeq; WP_010869383.1; NC_000908.2.
DR   AlphaFoldDB; P47467; -.
DR   SMR; P47467; -.
DR   STRING; 243273.MG_225; -.
DR   TCDB; 2.A.3.3.15; the amino acid-polyamine-organocation (apc) family.
DR   EnsemblBacteria; AAC71446; AAC71446; MG_225.
DR   KEGG; mge:MG_225; -.
DR   eggNOG; COG0531; Bacteria.
DR   HOGENOM; CLU_601059_0_0_14; -.
DR   OMA; FASIKWA; -.
DR   OrthoDB; 527053at2; -.
DR   BioCyc; MGEN243273:G1GJ2-271-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   Pfam; PF13520; AA_permease_2; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..489
FT                   /note="Uncharacterized protein MG225"
FT                   /id="PRO_0000210467"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        449..469
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        282..286
FT                   /note="IFKKA -> TLEDI (in Ref. 2; AAD10570)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   489 AA;  54766 MW;  CAFEEE4E83DDF8A9 CRC64;
     MGQINRKFSE KQFLLFVVNY IAGFGFIATA ISLFRLGPFS WLIFLLVSLV SLIVTLSFAR
     LSSIDSQNYG GPYLWAKKAV DKEKIAGRMF SFFTGWNNFI IGPLSAATAP LFILNSFSGI
     DGIRGNLVNT WILIAIGFSF YVLLAFISTK GTSLNKKLIA LFASVKWIVI LSALIVAIYV
     IARDGNGYSQ NNNLESGFFG RREISFAQIA TVFITFFYSY AGVEDISVMT PDVKTNNFRK
     ILIVSFIAVF LFYFIGIIIL NGLQNIAQRG GEANSIGNVA DIFKKAAGLG TLIFYGVGAL
     FNNVSTRLST IIANSRKILP LAYDNYLPSF FYKQNKKGEF QNAIWFTFGT TLIAMTLLVF
     IPLVASNFDF DNATEYAASV GSAATLLQYI FVFFIIFKFI YKKEPLYQKK WVKTTEELLF
     CLGTIVIVLM LLVYLFPVID GFSKWETKHT LTIVLYGVLS LIGLVLFLLQ EYKHKNKQNA
     NKQTTQTTV