ID   Y2262_ARATH             Reviewed;         286 AA.
AC   Q9SIU9; Q84X35; Q84X36;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0725 protein At2g20620;
GN   OrderedLocusNames=At2g20620; ORFNames=F23N11.6;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
RC   STRAIN=cv. Columbia;
RX   PubMed=12481096; DOI=10.1104/pp.010207;
RA   Xiao Y.-L., Malik M., Whitelaw C.A., Town C.D.;
RT   "Cloning and sequencing of cDNAs for hypothetical genes from chromosome 2
RT   of Arabidopsis.";
RL   Plant Physiol. 130:2118-2128(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q9SIU9-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q9SIU9-2; Sequence=VSP_036246;
CC       Name=3;
CC         IsoId=Q9SIU9-3; Sequence=VSP_036245;
CC   -!- SIMILARITY: Belongs to the UPF0725 (EMB2204) family. {ECO:0000305}.
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DR   EMBL; AC007048; AAD21705.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC07047.1; -; Genomic_DNA.
DR   EMBL; AY219069; AAO37156.1; -; mRNA.
DR   EMBL; AY219070; AAO37157.1; -; mRNA.
DR   EMBL; AY773847; AAV63876.1; -; mRNA.
DR   PIR; D84591; D84591.
DR   RefSeq; NP_179653.1; NM_127625.2. [Q9SIU9-1]
DR   AlphaFoldDB; Q9SIU9; -.
DR   SMR; Q9SIU9; -.
DR   PaxDb; Q9SIU9; -.
DR   PRIDE; Q9SIU9; -.
DR   EnsemblPlants; AT2G20620.1; AT2G20620.1; AT2G20620. [Q9SIU9-1]
DR   GeneID; 816588; -.
DR   Gramene; AT2G20620.1; AT2G20620.1; AT2G20620. [Q9SIU9-1]
DR   KEGG; ath:AT2G20620; -.
DR   Araport; AT2G20620; -.
DR   TAIR; locus:2046051; AT2G20620.
DR   HOGENOM; CLU_053767_2_3_1; -.
DR   InParanoid; Q9SIU9; -.
DR   OMA; GSLWRWD; -.
DR   OrthoDB; 1295742at2759; -.
DR   PhylomeDB; Q9SIU9; -.
DR   PRO; PR:Q9SIU9; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9SIU9; baseline and differential.
DR   Genevisible; Q9SIU9; AT.
DR   InterPro; IPR046350; Cystatin_sf.
DR   InterPro; IPR006462; MS5.
DR   PANTHER; PTHR31260; PTHR31260; 1.
DR   Pfam; PF04776; protein_MS5; 1.
DR   SUPFAM; SSF54403; SSF54403; 1.
DR   TIGRFAMs; TIGR01572; A_thl_para_3677; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..286
FT                   /note="UPF0725 protein At2g20620"
FT                   /id="PRO_0000363120"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..36
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         83..286
FT                   /note="GTNLELMTVTQVMLQSVAHINYHMILDAFDPANNSLSSIEICLWDAAVKNNE
FT                   KLRLVTTFCSLEGSGDKGSQWDPNGVDVLYTGVMPKWLDDGALSGSEKLHYYEVNDSDL
FT                   QENKWLHLYAQVGAYSKWDLGMVKHFPLEIKKVVVQTMEDDIESNLKLKSSNAIFYITF
FT                   TTSGGVECACIIRQTRNGRPQHMCLEINNVEMDK -> VTLIYIALILASPHLYFFFFF
FT                   GF (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:12481096"
FT                   /id="VSP_036245"
FT   VAR_SEQ         147..286
FT                   /note="GSGDKGSQWDPNGVDVLYTGVMPKWLDDGALSGSEKLHYYEVNDSDLQENKW
FT                   LHLYAQVGAYSKWDLGMVKHFPLEIKKVVVQTMEDDIESNLKLKSSNAIFYITFTTSGG
FT                   VECACIIRQTRNGRPQHMCLEINNVEMDK -> VCCRVWR (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12481096, ECO:0000303|Ref.4"
FT                   /id="VSP_036246"
SQ   SEQUENCE   286 AA;  31926 MW;  8151202B213204CC CRC64;
     MVLETPVCSP IDKESSSDDV QLNKPPKKKR KLDVVYPPRD NTSSSSDVKP KVPGYCGVKA
     IGCNRSDELL AEVALHSYNS QTGTNLELMT VTQVMLQSVA HINYHMILDA FDPANNSLSS
     IEICLWDAAV KNNEKLRLVT TFCSLEGSGD KGSQWDPNGV DVLYTGVMPK WLDDGALSGS
     EKLHYYEVND SDLQENKWLH LYAQVGAYSK WDLGMVKHFP LEIKKVVVQT MEDDIESNLK
     LKSSNAIFYI TFTTSGGVEC ACIIRQTRNG RPQHMCLEIN NVEMDK