ID   Y2266_STAAN             Reviewed;         231 AA.
AC   Q7A3L9;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Uncharacterized oxidoreductase SA2266;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SA2266;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=N315;
RA   Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.;
RT   "Shotgun proteomic analysis of total and membrane protein extracts of S.
RT   aureus strain N315.";
RL   Submitted (OCT-2007) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; BA000018; BAB43569.1; -; Genomic_DNA.
DR   PIR; G90050; G90050.
DR   RefSeq; WP_000217456.1; NC_002745.2.
DR   AlphaFoldDB; Q7A3L9; -.
DR   SMR; Q7A3L9; -.
DR   EnsemblBacteria; BAB43569; BAB43569; BAB43569.
DR   KEGG; sau:SA2266; -.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; ITGGRNW; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   1: Evidence at protein level;
KW   Oxidoreductase.
FT   CHAIN           1..231
FT                   /note="Uncharacterized oxidoreductase SA2266"
FT                   /id="PRO_0000300475"
FT   ACT_SITE        153
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         140
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   231 AA;  24578 MW;  EED1BCE261E87778 CRC64;
     MTVLTDKIAV VTGAGSGIGE AIATLLHEEG AKVVLAGRNK DKLQNVANQL AQDSVKVVPT
     DVTNKEEVDE LMKIAQQTFG GLDIVINSAG QMLSSKITDY QVDEWDSMID VNIKGTLYTA
     QAALPTMLEQ SSGHLINIAS ISGFEVTKSS TIYSATKAAV HTITQGLEKE LAKTGVKVTS
     ISPGMVDTAI TAAYNPSDRK KLDPQDIAEA VLYALTQPKH VNVNEITVRP V