ID   Y2267_ARCFU             Reviewed;         174 AA.
AC   O28017;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Putative NADH dehydrogenase/NAD(P)H nitroreductase AF_2267;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=AF_2267;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the nitroreductase family. {ECO:0000305}.
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DR   EMBL; AE000782; AAB88993.1; -; Genomic_DNA.
DR   PIR; C69533; C69533.
DR   RefSeq; WP_010879756.1; NC_000917.1.
DR   AlphaFoldDB; O28017; -.
DR   SMR; O28017; -.
DR   STRING; 224325.AF_2267; -.
DR   PRIDE; O28017; -.
DR   EnsemblBacteria; AAB88993; AAB88993; AF_2267.
DR   GeneID; 24796032; -.
DR   KEGG; afu:AF_2267; -.
DR   eggNOG; arCOG00288; Archaea.
DR   HOGENOM; CLU_070764_7_3_2; -.
DR   OMA; HPYAKML; -.
DR   OrthoDB; 121018at2157; -.
DR   PhylomeDB; O28017; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.109.10; -; 1.
DR   InterPro; IPR029479; Nitroreductase.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   InterPro; IPR026021; YdjA-like.
DR   Pfam; PF00881; Nitroreductase; 2.
DR   PIRSF; PIRSF000232; YdjA; 1.
DR   SUPFAM; SSF55469; SSF55469; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NAD; NADP; Oxidoreductase; Reference proteome.
FT   CHAIN           1..174
FT                   /note="Putative NADH dehydrogenase/NAD(P)H nitroreductase
FT                   AF_2267"
FT                   /id="PRO_0000072724"
FT   BINDING         107..112
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   174 AA;  20098 MW;  EA8517156D73253F CRC64;
     MEECLKMIYT RRSIRVYSDR QISDEDIEKI LKAAMLAPSA GNEQPWHFIV VRDREMLKKM
     SEAFTFGQML PNASAAIVVC ADPKLSKYPY DMWVQDCSAA TENILLAARC LGIGSVWLGV
     YPREERMKAL RELLGIPENI VVFSVVSLGY PKDEKDFYEA DDRFNPDRIH REKW