ID   Y226_TREPA              Reviewed;         228 AA.
AC   O83254;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Uncharacterized protein TP_0226;
GN   OrderedLocusNames=TP_0226;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65219.1; -; Genomic_DNA.
DR   PIR; H71350; H71350.
DR   RefSeq; WP_010881674.1; NC_021490.2.
DR   AlphaFoldDB; O83254; -.
DR   SMR; O83254; -.
DR   IntAct; O83254; 1.
DR   STRING; 243276.TPANIC_0226; -.
DR   PRIDE; O83254; -.
DR   EnsemblBacteria; AAC65219; AAC65219; TP_0226.
DR   KEGG; tpa:TP_0226; -.
DR   HOGENOM; CLU_1214345_0_0_12; -.
DR   OMA; MHAGYHI; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003339; ABC/ECF_trnsptr_transmembrane.
DR   Pfam; PF02361; CbiQ; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..228
FT                   /note="Uncharacterized protein TP_0226"
FT                   /id="PRO_0000202215"
FT   TRANSMEM        37..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   228 AA;  26203 MW;  71F8AD4EFB0EF6A5 CRC64;
     MFFSLYERRQ SLLHRAPPVA KVASFALLLL CCNAQSWCMH ASLTLVLLAL TLIVTRSLKC
     VAAHIRVVSI YLAFFFSLKI LHTFFSTGVV SATQINQHIH AGYHIGIRLF LLLCASSLFY
     ACTSRLELFS LCLRMGKVLH VRSTAYTTPC AVYVMMLVLY FGHDIFREWT ELRFVWRART
     RANTSFYNWV DATLHFSKTL LTRLLERAQH PSLRRADFKV SDNILSSE