ID   Y2271_ALKPO             Reviewed;         379 AA.
AC   O87557; D3FVC3;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 2.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=UPF0754 protein BpOF4_11355;
GN   OrderedLocusNames=BpOF4_11355;
OS   Alkalihalophilus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4)
OS   (Bacillus pseudofirmus).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalophilus.
OX   NCBI_TaxID=398511;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10356997; DOI=10.1007/s007920050106;
RA   Wei Y., Guffanti A.A., Krulwich T.A.;
RT   "Sequence analysis and functional studies of a chromosomal region of
RT   alkaliphilic Bacillus firmus OF4 encoding an ABC-type transporter with
RT   similarity of sequence and Na+ exclusion capacity to the Bacillus subtilis
RT   NatAB transporter.";
RL   Extremophiles 3:113-120(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2126 / JCM 17055 / OF4;
RX   PubMed=21951522; DOI=10.1111/j.1462-2920.2011.02591.x;
RA   Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J.,
RA   Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B.,
RA   Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G., Xue Y., Ma Y.,
RA   Hu F.Z., Krulwich T.A.;
RT   "Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that
RT   support the ability to grow in an external pH range from 7.5 to 11.4.";
RL   Environ. Microbiol. 13:3289-3309(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC62416.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AF084104; AAC62416.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP001878; ADC50324.1; -; Genomic_DNA.
DR   RefSeq; WP_012957690.1; NC_013791.2.
DR   AlphaFoldDB; O87557; -.
DR   STRING; 398511.BpOF4_11355; -.
DR   EnsemblBacteria; ADC50324; ADC50324; BpOF4_11355.
DR   KEGG; bpf:BpOF4_11355; -.
DR   eggNOG; COG4399; Bacteria.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   OrthoDB; 373600at2; -.
DR   Proteomes; UP000001544; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   InterPro; IPR016991; UCP032178.
DR   Pfam; PF04286; DUF445; 1.
DR   PIRSF; PIRSF032178; UCP032178; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..379
FT                   /note="UPF0754 protein BpOF4_11355"
FT                   /id="PRO_0000388281"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        359..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   379 AA;  43465 MW;  7E873C7DBD67C5B9 CRC64;
     MDTAWFIGFM VVIGAVIGGA TNSLAIKMLF RPYTEKRIGK WRVPFTPGLI PKRHQELAIQ
     LGHMVVHYLL TAEGLGKKLK SAVFMKAMND WLSTELLKLL RSELTIGELL EDKLGVKEPK
     QTLLQKTEGL IEKSYDRFFQ ENRYKQIGEV LPRGVNEKID HSVPVIAAFL LERGQALFSS
     EEGKERLSKM IDRFLLNKGT LGNMISMFLG NERLVDKLQP ELMKFMRDDG TKRMVEEILE
     KEWAKLKQKD VALIEDQLNK EDIVEYMTTA LEKNVTFYQW VDQPLCDWSE PFEDMLVINW
     VPKLVDAVSD LLALHLEGLL EKLNLEDIVR EQVEAFSVER LEELVLTISK REFKMITYLG
     ALLGGMIGFI QGLLVLFIG