ID   Y2272_MYCTU             Reviewed;         122 AA.
AC   P9WLF5; L0TAP7; P64969; Q50691;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Uncharacterized protein Rv2272;
GN   OrderedLocusNames=Rv2272; ORFNames=MTCY339.38c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To E.coli YidH. {ECO:0000305}.
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DR   EMBL; AL123456; CCP45053.1; -; Genomic_DNA.
DR   PIR; D70730; D70730.
DR   RefSeq; NP_216788.1; NC_000962.3.
DR   RefSeq; WP_003411674.1; NZ_NVQJ01000008.1.
DR   AlphaFoldDB; P9WLF5; -.
DR   STRING; 83332.Rv2272; -.
DR   PaxDb; P9WLF5; -.
DR   DNASU; 887459; -.
DR   GeneID; 45426254; -.
DR   GeneID; 887459; -.
DR   KEGG; mtu:Rv2272; -.
DR   TubercuList; Rv2272; -.
DR   eggNOG; COG2149; Bacteria.
DR   OMA; NHWVRCE; -.
DR   PhylomeDB; P9WLF5; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003807; DUF202.
DR   Pfam; PF02656; DUF202; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..122
FT                   /note="Uncharacterized protein Rv2272"
FT                   /id="PRO_0000103999"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   122 AA;  12994 MW;  23A53754264887A7 CRC64;
     MADDSNDTAT DVEPDYRFTL ANERTFLAWQ RTALGLLAAA VALVQLVPEL TIPGARQVLG
     VVLAILAILT SGMGLLRWQQ ADRAMRRHLP LPRHPTPGYL AVGLCVVGVV ALALVVAKAI
     TG