ID   Y2273_STAAN             Reviewed;         264 AA.
AC   Q7A3L3;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Uncharacterized lipoprotein SA2273;
DE   Flags: Precursor;
GN   OrderedLocusNames=SA2273;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=N315;
RA   Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.;
RT   "Shotgun proteomic analysis of total and membrane protein extracts of S.
RT   aureus strain N315.";
RL   Submitted (OCT-2007) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the staphylococcal tandem lipoprotein family.
CC       {ECO:0000305}.
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DR   EMBL; BA000018; BAB43576.1; -; Genomic_DNA.
DR   PIR; F90051; F90051.
DR   RefSeq; WP_000581871.1; NC_002745.2.
DR   AlphaFoldDB; Q7A3L3; -.
DR   SMR; Q7A3L3; -.
DR   EnsemblBacteria; BAB43576; BAB43576; BAB43576.
DR   KEGG; sau:SA2273; -.
DR   HOGENOM; CLU_071589_0_0_9; -.
DR   OMA; WIIHSEM; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.50.20.40; -; 1.
DR   InterPro; IPR007595; Csa.
DR   InterPro; IPR038641; Csa_sf.
DR   Pfam; PF04507; DUF576; 1.
DR   TIGRFAMs; TIGR01742; SA_tandem_lipo; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..264
FT                   /note="Uncharacterized lipoprotein SA2273"
FT                   /id="PRO_0000282139"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   264 AA;  30832 MW;  C9D99CF26C215BA2 CRC64;
     MIHSKKLTLG ICLVLLIILI GGCIIMTKIN SRNAQIKDTF NQTLNVYPTK NLDDFYDKEG
     FRDQEFDKRD KGTWIINSGM YIQLKGGALK SRAMVLYINR NTRTAKGYFL ISETTEDKKG
     YVHNKDKKYP VKMERNRIIP TKPITDEKLK KEIENFKFFV QYGNFKDFKD YKDGDISYNP
     NVPSYSAKYQ LNNDDYNVQQ LRKRYDISTK RAPELKLRGS GDLKGSSVGS KELEFNFVRN
     KEENVYFSDG INFKPTEEMN HEQN