ID   Y2293_MYCTO             Reviewed;         246 AA.
AC   P9WLE0; L0T9E0; Q50673;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Uncharacterized protein MT2350;
DE   Flags: Precursor;
GN   OrderedLocusNames=MT2350;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Multi-pass membrane protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000516; AAK46635.1; -; Genomic_DNA.
DR   PIR; A70733; A70733.
DR   RefSeq; WP_003899254.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WLE0; -.
DR   SMR; P9WLE0; -.
DR   EnsemblBacteria; AAK46635; AAK46635; MT2350.
DR   KEGG; mtc:MT2350; -.
DR   PATRIC; fig|83331.31.peg.2529; -.
DR   HOGENOM; CLU_074334_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1580; -; 1.
DR   InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR   InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR   Pfam; PF01048; PNP_UDP_1; 1.
DR   SUPFAM; SSF53167; SSF53167; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           25..246
FT                   /note="Uncharacterized protein MT2350"
FT                   /id="PRO_0000427495"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   246 AA;  25255 MW;  35710591F556A4A0 CRC64;
     MGAPLRHCLL VAAALSLGCG VAAADPGYVA NVIPCEQRTL VLSAFPAEAD AVLAHTALDA
     NPVVVADRRR YYLGSISGKK VIVAMTGIGL VNATNTTETA FARFTCASSI AIAAVMFSGV
     AGGAGRTSIG DVAIPARWTL DNGATFRGVD PGMLATAQTL SVVLDNINTL GNPVCLCRNV
     PVVRLNHLGR QPQLFVGGDG SSSDKNNGQA FPCIPNGGSV FAANPVVHPI AHLAIPVTFS
     RRRDPG