ID   Y2299_ANOFW             Reviewed;         369 AA.
AC   B7GF17;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 2.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=UPF0754 membrane protein Aflv_2299;
GN   OrderedLocusNames=Aflv_2299;
OS   Anoxybacillus flavithermus (strain DSM 21510 / WK1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Anoxybacillus.
OX   NCBI_TaxID=491915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21510 / WK1;
RX   PubMed=19014707; DOI=10.1186/gb-2008-9-11-r161;
RA   Saw J.H., Mountain B.W., Feng L., Omelchenko M.V., Hou S., Saito J.A.,
RA   Stott M.B., Li D., Zhao G., Wu J., Galperin M.Y., Koonin E.V.,
RA   Makarova K.S., Wolf Y.I., Rigden D.J., Dunfield P.F., Wang L., Alam M.;
RT   "Encapsulated in silica: genome, proteome and physiology of the
RT   thermophilic bacterium Anoxybacillus flavithermus WK1.";
RL   Genome Biol. 9:R161.1-R161.16(2008).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACJ34656.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000922; ACJ34656.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041638879.1; NC_011567.1.
DR   AlphaFoldDB; B7GF17; -.
DR   STRING; 491915.Aflv_2299; -.
DR   EnsemblBacteria; ACJ34656; ACJ34656; Aflv_2299.
DR   KEGG; afl:Aflv_2299; -.
DR   PATRIC; fig|491915.6.peg.2367; -.
DR   eggNOG; COG4399; Bacteria.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   OrthoDB; 373600at2; -.
DR   Proteomes; UP000000742; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   InterPro; IPR016991; UCP032178.
DR   Pfam; PF04286; DUF445; 1.
DR   PIRSF; PIRSF032178; UCP032178; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..369
FT                   /note="UPF0754 membrane protein Aflv_2299"
FT                   /id="PRO_0000388263"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   369 AA;  43242 MW;  D17206807E257AA4 CRC64;
     MGLFLYLLFM IVVGAFIGGM TNSLAIKMLF RPYRPIYIAG KRLPFTPGLI PKRREELAEQ
     LGRMVVEHLL TAEGLRRKLN DPSFVQDMTS YVQEEVEKWL QSDRTVEQWL KQFGMPDPKQ
     TAETWIETKY KTFMSQYRQR PLHEIIPIDV LHKIDHAIPS IVDRLLLRLR TYIESEQGER
     QIEHMINEFL QSRGMFGNML QMFLGNVSLA EKIRPEIVKF LQSEGAKQLL VQLFINEWEK
     VKEMRIHEVE QIIDQEKIVV WVKRLTASIV QEPLQKPLGA LVAPYVRHSL PTLVRFLLQF
     ASERIERWMK QLHLQDIVRE EVASFSVERL EEMILTISRR EFKMITYLGA LLGGIIGLIQ
     GCITFFVQM