ID   Y229_MYCBO              Reviewed;         254 AA.
AC   Q7U2J0; A0A1R3XUV7; X2BEA5;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Uncharacterized methyltransferase Mb0229c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=BQ2027_MB0229C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND INDUCTION.
RC   STRAIN=BCG / Pasteur;
RX   PubMed=16006064; DOI=10.1016/j.femsle.2005.06.004;
RA   Dosanjh N.S., Rawat M., Chung J.-H., Av-Gay Y.;
RT   "Thiol specific oxidative stress response in Mycobacteria.";
RL   FEMS Microbiol. Lett. 249:87-94(2005).
CC   -!- INDUCTION: Induced in response to the thiol oxidant diamide.
CC       {ECO:0000269|PubMed:16006064}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; LT708304; SIT98717.1; -; Genomic_DNA.
DR   RefSeq; NP_853894.1; NC_002945.3.
DR   RefSeq; WP_010950364.1; NC_002945.4.
DR   AlphaFoldDB; Q7U2J0; -.
DR   SMR; Q7U2J0; -.
DR   PATRIC; fig|233413.5.peg.255; -.
DR   OMA; TNWLSPW; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   1: Evidence at protein level;
KW   Methyltransferase; Transferase.
FT   CHAIN           1..254
FT                   /note="Uncharacterized methyltransferase Mb0229c"
FT                   /id="PRO_0000380598"
SQ   SEQUENCE   254 AA;  27476 MW;  0FA10E661D3D2169 CRC64;
     MAVTDVFARR ATLRRSLRLL ADFRYEQRDP ARFYRTLAAD TAAMIGDLWL ATHSEPPVGR
     TLLDVGGGPG YFATAFSDAG VGYIGVEPDP DEMHAAGPAF TGRPGMFVRA SGMALPLADD
     SVDICLSSNV AEHVPRPWQL GTEMLRVTKP GGLVVLSYTV WLGPFGGHEM GLSHYLGGAR
     AAARYVRKHG HPAKNNYGSS LFAVSAAEGL RWAAGTGAAL AVFPRYHPRW AWWLTSVPVL
     REFLVSNLVL VLTP