ID   Y2300_METMA             Reviewed;         230 AA.
AC   Q8PUN2;
DT   10-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   10-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=UPF0173 metal-dependent hydrolase MM_2300 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=MM_2300;
OS   Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS   11833 / OCM 88) (Methanosarcina frisia).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=192952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RX   PubMed=12125824;
RA   Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA   Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C.,
RA   Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S.,
RA   Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P.,
RA   Fritz H.-J., Gottschalk G.;
RT   "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT   between Bacteria and Archaea.";
RL   J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AE008384; AAM31996.1; -; Genomic_DNA.
DR   RefSeq; WP_011034225.1; NC_003901.1.
DR   AlphaFoldDB; Q8PUN2; -.
DR   SMR; Q8PUN2; -.
DR   STRING; 192952.MM_2300; -.
DR   DNASU; 1480642; -.
DR   EnsemblBacteria; AAM31996; AAM31996; MM_2300.
DR   GeneID; 1480642; -.
DR   KEGG; mma:MM_2300; -.
DR   PATRIC; fig|192952.21.peg.2635; -.
DR   eggNOG; arCOG00497; Archaea.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   OMA; WHGHSTW; -.
DR   Proteomes; UP000000595; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..230
FT                   /note="UPF0173 metal-dependent hydrolase MM_2300"
FT                   /id="PRO_0000156396"
SQ   SEQUENCE   230 AA;  24933 MW;  3D69CD56DE8BA21A CRC64;
     MADLKITWLG HAAFLLESEK KLLIDPFISE NPKSPCSPED LNPDIIAVTH GHRDHLGDTI
     EIGARTGCRI ISIHEVANYI KSKGVFAEGM NKGGTVEVEG IALTMTHALH SSSIDASGFS
     FDGGSPAGFV INIGGYSVYH SGDTGVFGDM QLIGELYKPE IALLPIGSRF TMGIKEAVKA
     VELIEPRIVV PMHYNTFDVI RQDPEEFRKA VEAKVDTKVI IMSPGESIQL