Y2302_MYCBO
ID Y2302_MYCBO Reviewed; 552 AA.
AC P65713; A0A1R3Y2W6; Q50684; X2BK88;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Putative phosphate permease Mb2302;
GN OrderedLocusNames=BQ2027_MB2302;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- FUNCTION: Potential transporter for phosphate.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC 2.A.20) family. {ECO:0000305}.
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DR EMBL; LT708304; SIU00914.1; -; Genomic_DNA.
DR RefSeq; NP_855951.1; NC_002945.3.
DR RefSeq; WP_003411694.1; NC_002945.4.
DR AlphaFoldDB; P65713; -.
DR SMR; P65713; -.
DR EnsemblBacteria; SIU00914; SIU00914; BQ2027_MB2302.
DR GeneID; 45426261; -.
DR PATRIC; fig|233413.5.peg.2527; -.
DR OMA; MQAFCIA; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR001204; Phos_transporter.
DR PANTHER; PTHR11101; PTHR11101; 1.
DR Pfam; PF01384; PHO4; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Phosphate transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..552
FT /note="Putative phosphate permease Mb2302"
FT /id="PRO_0000080802"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 437..457
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 493..513
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 552 AA; 58789 MW; 050847C107DA3716 CRC64;
MSDNAKHHRD GHLVASGLQD RAARTPQHEG FLGPDRPWHL SFSLLLAGSF VLFSWWAFDY
AGSGANKVIL VLATVVGMFM AFNVGGNDVA NSFGTSVGAG TLTMKQALLV AAIFEVSGAV
IAGGDVTETI RSGIVDLSGV SVDPRDFMNI MLSALSAAAL WLLFANRMGY PVSTTHSIIG
GIVGAAIALG MVSGQGGAAL RMVQWDQIGQ IVVSWVLSPV LGGLVSYLLY GVIKRHILLY
NEQAERRLTE IKKERIAHRE RHKAAFDRLT EIQQIAYTGA LARDAVAANR KDFDPDELES
DYYRELHEID AKTSSVDAFR ALQNWVPLVA AAGSMIIVAM LLFKGFKHMH LGLTTMNNYF
IIAMVGAAVW MATFIFAKTL RGESLSRSTF LMFSWMQVFT ASGFAFSHGS NDIANAIGPF
AAILDVLRTG AIEGNAAVPA AAMVTFGVAL CAGLWFIGRR VIATVGHNLT TMHPASGFAA
ELSAAGVVMG ATVLGLPVSS THILIGAVLG VGIVNRSTNW GLMKPIVLAW VITLPSAAIL
ASVGLVALRA IF