ID   Y2318_METBF             Reviewed;         327 AA.
AC   Q46A50;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein Mbar_A2318 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=Mbar_A2318;
OS   Methanosarcina barkeri (strain Fusaro / DSM 804).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=269797;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fusaro / DSM 804;
RX   PubMed=16980466; DOI=10.1128/jb.00810-06;
RA   Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S.,
RA   Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.;
RT   "The Methanosarcina barkeri genome: comparative analysis with
RT   Methanosarcina acetivorans and Methanosarcina mazei reveals extensive
RT   rearrangement within methanosarcinal genomes.";
RL   J. Bacteriol. 188:7922-7931(2006).
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DR   EMBL; CP000099; AAZ71242.1; -; Genomic_DNA.
DR   RefSeq; WP_011307288.1; NC_007355.1.
DR   AlphaFoldDB; Q46A50; -.
DR   SMR; Q46A50; -.
DR   STRING; 269797.Mbar_A2318; -.
DR   EnsemblBacteria; AAZ71242; AAZ71242; Mbar_A2318.
DR   GeneID; 3625226; -.
DR   KEGG; mba:Mbar_A2318; -.
DR   eggNOG; arCOG04152; Archaea.
DR   HOGENOM; CLU_075726_0_0_2; -.
DR   OMA; PGVVYFR; -.
DR   OrthoDB; 76134at2157; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..327
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   Mbar_A2318"
FT                   /id="PRO_0000259359"
FT   DOMAIN          132..190
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        143..162
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   327 AA;  36538 MW;  502C11BF1753E2B6 CRC64;
     MTKEVLIHQI IDVLARAGFA LSDRCNIRPR SFDVAARKDE TLLLCKVLFN IDGLNEETAR
     EMKYLAEYLG GSAIVVGAKT RDQMLEDSVV YMRYDILALN VQTLYDYFIE NVPPLVSAAP
     GGLYVSIEGD ILKKARMGQS MSLGTLASMV GVSRRTISKY EEEGMDASID VVLQLEDIFG
     VELAKPINIL KSCGSRKPRK KAESRTETQE KPYTLLPEDL ILNTISMLGY DVLPTTQAPF
     KAISRDKSSV ILTGVSEFNT TVVKRAHLMS SISCVTETQS VFIINGHSKI KSVENTVMIE
     KKELDKISDS QELLNFIEER RETHDEK