ID   Y2320_MYCBO             Reviewed;         323 AA.
AC   P63485; A0A1R3Y0T9; Q50668; X2BKP9;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Uncharacterized oxidoreductase Mb2320;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=BQ2027_MB2320;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family. Aldo/keto
CC       reductase 2 subfamily. {ECO:0000305}.
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DR   EMBL; LT708304; SIU00932.1; -; Genomic_DNA.
DR   RefSeq; NP_855969.1; NC_002945.3.
DR   RefSeq; WP_003902161.1; NC_002945.4.
DR   AlphaFoldDB; P63485; -.
DR   SMR; P63485; -.
DR   EnsemblBacteria; SIU00932; SIU00932; BQ2027_MB2320.
DR   GeneID; 45426278; -.
DR   PATRIC; fig|233413.5.peg.2544; -.
DR   OMA; CGTWAWG; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.100; -; 1.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; SSF51430; 1.
PE   3: Inferred from homology;
KW   NADP; Oxidoreductase.
FT   CHAIN           1..323
FT                   /note="Uncharacterized oxidoreductase Mb2320"
FT                   /id="PRO_0000070397"
FT   ACT_SITE        59
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   BINDING         198..208
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   323 AA;  34986 MW;  FF071A48B745B8E8 CRC64;
     MKYLDVDGIG QVSRIGLGTW QFGSREWGYG DRYATGAARD IVKRARALGV TLFDTAEIYG
     LGKSERILGE ALGDDRTEVV VASKVFPVAP FPAVIKNRER ASARRLQLNR IPLYQIHQPN
     PVVPDSVIMP GMRDLLDSGD IGAAGVSNYS LARWRKADAA LGRPVVSNQV HFSLAHPDAL
     EDLVPFAELE NRIVIAYSPL AQGLLGGKYG LENRPGGVRA LNPLFGTENL RRIEPLLATL
     RAIAVDVDAK PAQVALAWLI SLPGVVAIPG ASSVEQLEFN VAAADIELSA QSRDALTDAA
     RAFRPVSTGR FLTDMVREKV SRR