ID   Y2323_STAA1             Reviewed;         108 AA.
AC   A7X5U9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=UPF0060 membrane protein SAHV_2323 {ECO:0000255|HAMAP-Rule:MF_00010};
GN   OrderedLocusNames=SAHV_2323;
OS   Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=418127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu3 / ATCC 700698;
RX   PubMed=17954695; DOI=10.1128/aac.00534-07;
RA   Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT   "Mutated response regulator graR is responsible for phenotypic conversion
RT   of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT   resistance to vancomycin-intermediate resistance.";
RL   Antimicrob. Agents Chemother. 52:45-53(2008).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00010};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00010}.
CC   -!- SIMILARITY: Belongs to the UPF0060 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00010}.
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DR   EMBL; AP009324; BAF79206.1; -; Genomic_DNA.
DR   RefSeq; WP_000966695.1; NZ_CTYB01000041.1.
DR   AlphaFoldDB; A7X5U9; -.
DR   KEGG; saw:SAHV_2323; -.
DR   HOGENOM; CLU_117653_0_1_9; -.
DR   OMA; WLWAVEG; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_00010; UPF0060; 1.
DR   InterPro; IPR003844; UPF0060.
DR   PANTHER; PTHR36116; PTHR36116; 1.
DR   Pfam; PF02694; UPF0060; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..108
FT                   /note="UPF0060 membrane protein SAHV_2323"
FT                   /id="PRO_1000000767"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
SQ   SEQUENCE   108 AA;  11758 MW;  A17ECCB10D262ABC CRC64;
     MLYPIFIFIL AGLCEIGGGY LIWLWLREGQ SSLVGLIGGA ILMLYGVIAT FQSFPSFGRV
     YAAYGGVFII MSLIFAMVVD KQMPDKYDVI GAIICIVGVL VMLLPSRA