ID   Y2324_STRCO             Reviewed;         563 AA.
AC   Q9KXJ6;
DT   21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Putative ABC transporter ATP-binding protein SCO2324;
DE            EC=7.-.-.-;
GN   OrderedLocusNames=SCO2324; ORFNames=SCC53.15;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- FUNCTION: Probably part of an ABC transporter complex. Responsible for
CC       energy coupling to the transport system (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; AL939112; CAB93444.1; -; Genomic_DNA.
DR   RefSeq; NP_626571.1; NC_003888.3.
DR   RefSeq; WP_011028281.1; NZ_VNID01000001.1.
DR   AlphaFoldDB; Q9KXJ6; -.
DR   SMR; Q9KXJ6; -.
DR   STRING; 100226.SCO2324; -.
DR   TCDB; 3.A.1.32.1; the atp-binding cassette (abc) superfamily.
DR   GeneID; 1097758; -.
DR   KEGG; sco:SCO2324; -.
DR   PATRIC; fig|100226.15.peg.2361; -.
DR   eggNOG; COG3845; Bacteria.
DR   HOGENOM; CLU_000604_86_7_11; -.
DR   InParanoid; Q9KXJ6; -.
DR   OMA; LAYGMEQ; -.
DR   PhylomeDB; Q9KXJ6; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   CDD; cd03225; ABC_cobalt_CbiO_domain1; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Repeat; Translocase; Transport.
FT   CHAIN           1..563
FT                   /note="Putative ABC transporter ATP-binding protein
FT                   SCO2324"
FT                   /id="PRO_0000092092"
FT   DOMAIN          2..243
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          317..545
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          271..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        278..294
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         349..356
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   563 AA;  59587 MW;  FFC8477F9F7FB48F CRC64;
     MIRFEDVSVT YDGATEPTVR AVDFEVPEGE LVLLAGPSGV GKSTVLGAVG GLVPHFTGGT
     LRGRVTVAGR DTRTHKPREL ADVVGTVGQD PLSHFVTDTV EDELAYGMES LGLPPDVMRR
     RVEETLDLLG LSDLRSRPIA TLSGGQQQRV AIGSVLTPHP DVLVLDEPTS ALDPAAAEEV
     LAVLQRLVHD LGTTVLMAEH RLERVIQYAD QVVLLPAPGE APLIGAPAEV MAVSPVYPPV
     VGLGRLAGWS PLPLTIRNAR RRAAPLRERL AGREIPDHTP PPSAPLPAPP APRPVTSRWR
     RRGKRPENPS APTPYAAEVR SLAVRRDRVQ ALRHVDLTVS PGETVALMGR NGAGKSTLLS
     ALVGLVEPSA GSVRAGDAVP HRTAPRDLVR RVGLVPQEPR DLLYADTVAA ECAAADRDAD
     AAPGTCRALL SELLPGITDD IHPRDLSEGQ RLTLALSVVL TARPPLLLLD EPTRGLDYAA
     KARLAGILRG LAAEGHAIVL ATHDVELAAE LAHRVVLLAE GEVIADGPAA DVVVASPSYA
     PQVAKVLAPR KWLTVAQVRE ALT