ID   Y232_MYCTA              Reviewed;         254 AA.
AC   A5TYU9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Uncharacterized methyltransferase MRA_0232;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MRA_0232;
OS   Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=419947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25177 / H37Ra;
RX   PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA   Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA   Wang H., Wang S., Zhao G., Zhang Y.;
RT   "Genetic basis of virulence attenuation revealed by comparative genomic
RT   analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL   PLoS ONE 3:E2375-E2375(2008).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; CP000611; ABQ71949.1; -; Genomic_DNA.
DR   RefSeq; WP_003401240.1; NZ_CP016972.1.
DR   AlphaFoldDB; A5TYU9; -.
DR   STRING; 419947.MRA_0232; -.
DR   EnsemblBacteria; ABQ71949; ABQ71949; MRA_0232.
DR   KEGG; mra:MRA_0232; -.
DR   eggNOG; COG0500; Bacteria.
DR   HOGENOM; CLU_073035_0_0_11; -.
DR   OMA; TNWLSPW; -.
DR   OrthoDB; 1515497at2; -.
DR   Proteomes; UP000001988; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Transferase.
FT   CHAIN           1..254
FT                   /note="Uncharacterized methyltransferase MRA_0232"
FT                   /id="PRO_0000380609"
SQ   SEQUENCE   254 AA;  27511 MW;  E2C4C10EBF3D2161 CRC64;
     MAVTDVFARR ATLRRSLRLL ADFRYEQRDP ARFYRTLAAD TAAMIGDLWL ATHSEPPVGR
     TLLDVGGGPG YFATAFSDAG VGYIGVEPDP DEMHAAGPAF TGRPGMFVRA SGMALPFADD
     SVDICLSSNV AEHVPRPWQL GTEMLRVTKP GGLVVLSYTV WLGPFGGHEM GLSHYLGGAR
     AAARYVRKHG HPAKNNYGSS LFAVSAAEGL RWAAGTGAAL AVFPRYHPRW AWWLTSVPVL
     REFLVSNLVL VLTP