ID   Y2330_MYCLE             Reviewed;         116 AA.
AC   O69519;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Nucleoid-associated protein ML2330 {ECO:0000255|HAMAP-Rule:MF_00274};
GN   OrderedLocusNames=ML2330; ORFNames=MLCB2407.20;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC       regulation of gene expression, nucleoid organization and DNA
CC       protection. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
CC   -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
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DR   EMBL; AL023596; CAA19160.1; -; Genomic_DNA.
DR   EMBL; AL583925; CAC31846.1; -; Genomic_DNA.
DR   PIR; F87200; F87200.
DR   RefSeq; NP_302516.1; NC_002677.1.
DR   RefSeq; WP_010908836.1; NC_002677.1.
DR   AlphaFoldDB; O69519; -.
DR   SMR; O69519; -.
DR   STRING; 272631.ML2330; -.
DR   EnsemblBacteria; CAC31846; CAC31846; CAC31846.
DR   KEGG; mle:ML2330; -.
DR   PATRIC; fig|272631.5.peg.4459; -.
DR   Leproma; ML2330; -.
DR   eggNOG; COG0718; Bacteria.
DR   HOGENOM; CLU_140930_4_0_11; -.
DR   OMA; MGNMMKQ; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1310.10; -; 1.
DR   HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR   InterPro; IPR036894; YbaB-like_sf.
DR   InterPro; IPR004401; YbaB/EbfC.
DR   PANTHER; PTHR33449; PTHR33449; 1.
DR   Pfam; PF02575; YbaB_DNA_bd; 1.
DR   PIRSF; PIRSF004555; UCP004555; 1.
DR   SUPFAM; SSF82607; SSF82607; 1.
DR   TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome.
FT   CHAIN           1..116
FT                   /note="Nucleoid-associated protein ML2330"
FT                   /id="PRO_0000170411"
FT   REGION          96..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..116
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   116 AA;  11932 MW;  E4DAE4940AA76059 CRC64;
     MQPGGDMSAL LAQAQQMQQK LLETQQQLAN AQVHGQGGGG LVEVVVKGSG EVVSVAIDPK
     VVDPGDIETL QDLIVGAMAD ASKQVTKLAQ ERLGALTSAM RPTAPPPTPP TYMAGT