ID   Y2336_CANAL             Reviewed;         202 AA.
AC   Q59WG5; A0A1D8PEZ8;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Probable pathogenesis-related protein CaO19.2336;
DE   Flags: Precursor;
GN   OrderedLocusNames=CAALFM_C110810WA; ORFNames=CaO19.2336, CaO19.9872;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
RN   [4]
RP   IDENTIFICATION, AND INDUCTION.
RX   PubMed=23136884; DOI=10.1111/mmi.12087;
RA   Rohm M., Lindemann E., Hiller E., Ermert D., Lemuth K., Trkulja D.,
RA   Sogukpinar O., Brunner H., Rupp S., Urban C.F., Sohn K.;
RT   "A family of secreted pathogenesis-related proteins in Candida albicans.";
RL   Mol. Microbiol. 87:132-151(2013).
CC   -!- FUNCTION: Secreted protein that acts as a virulence factor during
CC       infections. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- INDUCTION: Expression is higher in white cells.
CC       {ECO:0000269|PubMed:23136884}.
CC   -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW26708.1; -; Genomic_DNA.
DR   RefSeq; XP_713941.1; XM_708848.1.
DR   AlphaFoldDB; Q59WG5; -.
DR   SMR; Q59WG5; -.
DR   BioGRID; 1227484; 1.
DR   STRING; 237561.Q59WG5; -.
DR   GeneID; 3644436; -.
DR   KEGG; cal:CAALFM_C110810WA; -.
DR   CGD; CAL0000186053; orf19.9872.
DR   VEuPathDB; FungiDB:C1_10810W_A; -.
DR   eggNOG; KOG3017; Eukaryota.
DR   HOGENOM; CLU_035730_6_4_1; -.
DR   InParanoid; Q59WG5; -.
DR   OMA; NNMFREN; -.
DR   OrthoDB; 1528782at2759; -.
DR   PRO; PR:Q59WG5; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   Gene3D; 3.40.33.10; -; 1.
DR   InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   PANTHER; PTHR10334; PTHR10334; 1.
DR   Pfam; PF00188; CAP; 1.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SUPFAM; SSF55797; SSF55797; 1.
DR   PROSITE; PS01010; CRISP_2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Secreted; Signal; Virulence.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..202
FT                   /note="Probable pathogenesis-related protein CaO19.2336"
FT                   /id="PRO_0000429962"
FT   DOMAIN          66..179
FT                   /note="SCP"
FT   CARBOHYD        58
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        152
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   202 AA;  22667 MW;  2AFE68EC875569E0 CRC64;
     MKTLLFIYLQ LLLLLSIIIG RVVKVEYLHL VVEVEPSTIT ESCLSDGIDG YSGSFYLNTT
     FAELMLKEHN NKRKLHQSCP LKWSSELFNY ASQFAAEYSC SGILQHSGGK YGENLAFGYS
     PIGAIEAWYD EGEMYVYGSE NVYNHFTAIV WNNTNSLGCA YKSCDTTTNL NALYIVCSYY
     PPGNVIGYSS QNVFPLNSKM VN