ID   Y2337_NATTJ             Reviewed;         222 AA.
AC   B2A8L8;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=UPF0173 metal-dependent hydrolase Nther_2337 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=Nther_2337;
OS   Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS   JW/NM-WN-LF).
OC   Bacteria; Firmicutes; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC   Natranaerobius.
OX   NCBI_TaxID=457570;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT   "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT   LF.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001034; ACB85902.1; -; Genomic_DNA.
DR   RefSeq; WP_012448752.1; NC_010718.1.
DR   AlphaFoldDB; B2A8L8; -.
DR   SMR; B2A8L8; -.
DR   STRING; 457570.Nther_2337; -.
DR   EnsemblBacteria; ACB85902; ACB85902; Nther_2337.
DR   KEGG; nth:Nther_2337; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_070010_4_1_9; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 767622at2; -.
DR   Proteomes; UP000001683; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..222
FT                   /note="UPF0173 metal-dependent hydrolase Nther_2337"
FT                   /id="PRO_0000367193"
SQ   SEQUENCE   222 AA;  24192 MW;  9E62FD74C3D77DCB CRC64;
     MKLEFIGHGC VQLSEGDDKI IFDPFIDDNP VAKISSSDVS PNYILLTHYH DDHKGDALEI
     AKDNDSLLIS TAEIAGAAEQ KGVKAHPMHI GGTKEFDFGK VRVTPALHGS GIDGGLACGF
     VVDFHGKKVY HAGDTGLFSD MKLISELEEI DIAILPIGGN FTMGAEEAVM ATQYLKPKAV
     MPVHYNTWPL IPADDEQFKK DIQEKTNSEC FVLEPGDSME MN