ID   Y2347_YERPE             Reviewed;         353 AA.
AC   Q8ZE38; Q0WEH4;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=UPF0283 membrane protein YPO2347/y1985/YP_2134 {ECO:0000255|HAMAP-Rule:MF_01085};
GN   OrderedLocusNames=YPO2347, y1985, YP_2134;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01085}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01085}.
CC   -!- SIMILARITY: Belongs to the UPF0283 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01085}.
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DR   EMBL; AL590842; CAL20975.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM85551.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS62343.1; -; Genomic_DNA.
DR   PIR; AD0286; AD0286.
DR   RefSeq; WP_002210980.1; NZ_WUCM01000120.1.
DR   RefSeq; YP_002347314.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZE38; -.
DR   IntAct; Q8ZE38; 2.
DR   STRING; 214092.YPO2347; -.
DR   PaxDb; Q8ZE38; -.
DR   DNASU; 1146932; -.
DR   EnsemblBacteria; AAM85551; AAM85551; y1985.
DR   EnsemblBacteria; AAS62343; AAS62343; YP_2134.
DR   GeneID; 66841304; -.
DR   KEGG; ype:YPO2347; -.
DR   KEGG; ypk:y1985; -.
DR   KEGG; ypm:YP_2134; -.
DR   PATRIC; fig|214092.21.peg.2753; -.
DR   eggNOG; COG3768; Bacteria.
DR   HOGENOM; CLU_057693_2_0_6; -.
DR   OMA; MFFIAWR; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   HAMAP; MF_01085; UPF0283; 1.
DR   InterPro; IPR021147; DUF697.
DR   InterPro; IPR006507; UPF0283.
DR   PANTHER; PTHR39342; PTHR39342; 1.
DR   Pfam; PF05128; DUF697; 1.
DR   TIGRFAMs; TIGR01620; hyp_HI0043; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..353
FT                   /note="UPF0283 membrane protein YPO2347/y1985/YP_2134"
FT                   /id="PRO_0000214192"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01085"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01085"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01085"
SQ   SEQUENCE   353 AA;  39264 MW;  852EA98A9E6FBB1E CRC64;
     MSEPLKPRID FEQPLQSLDE PVLKSAQAFD EQAAEKFYPA APELDAEDEE GRVEGLVNAA
     LKPKRSLWRK MVTAGMVILG ASVIAQSVQW VNQAWQQQDW IALGATTAGG LIILAGVGSV
     VTEWRRLYHL RQRAEERDIA RALLVSHGVG QGRVFCEKLA RQAGLDQGHP ALQRWQASLH
     ETHNDREVVE LYAKLVQPAL DNQARAEISR YAAESALMIA VSPLALVDMA FIAWRNIRLI
     NRIAALYGIE LGYFSRIRLF RLVLLNIAFA GASELVREVG MDWLSQDLAA RLSARAAQGI
     GAGLLTARLG IKAMELCRPL PWLEGDKPKL GDFRRQLMNQ LKNTLPKKDK TAH