ID   Y2348_MYCLE             Reviewed;         421 AA.
AC   Q49929;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Uncharacterized glycosyltransferase ML2348;
DE            EC=2.4.-.-;
GN   OrderedLocusNames=ML2348; ORFNames=L518_C2_147, MLCB2407.02c;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 28 family.
CC       {ECO:0000305}.
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DR   EMBL; U00023; AAA17353.1; -; Genomic_DNA.
DR   EMBL; AL023596; CAA19142.1; -; Genomic_DNA.
DR   EMBL; AL583925; CAC31864.1; -; Genomic_DNA.
DR   PIR; S73010; S73010.
DR   RefSeq; NP_302527.1; NC_002677.1.
DR   RefSeq; WP_010908847.1; NC_002677.1.
DR   AlphaFoldDB; Q49929; -.
DR   SMR; Q49929; -.
DR   STRING; 272631.ML2348; -.
DR   CAZy; GT1; Glycosyltransferase Family 1.
DR   EnsemblBacteria; CAC31864; CAC31864; CAC31864.
DR   KEGG; mle:ML2348; -.
DR   PATRIC; fig|272631.5.peg.4507; -.
DR   Leproma; ML2348; -.
DR   eggNOG; COG1819; Bacteria.
DR   HOGENOM; CLU_000537_8_0_11; -.
DR   OMA; GFPLFND; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR   GO; GO:0033072; P:vancomycin biosynthetic process; IEA:UniProt.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   InterPro; IPR004276; GlycoTrans_28_N.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   Pfam; PF03033; Glyco_transf_28; 1.
DR   Pfam; PF00201; UDPGT; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..421
FT                   /note="Uncharacterized glycosyltransferase ML2348"
FT                   /id="PRO_0000215625"
SQ   SEQUENCE   421 AA;  45929 MW;  0784E5F594EEB059 CRC64;
     MKFTLAASGS RGDVEPFAAL GLELQRRGHE VRIGVPPDML RFVESAGLAA VAYGPDTQEF
     LARDTYSQWR QWWKILPPIK ALQQLRQAWA DMATDLKSLA DGADLVMTGV VYQGVVANVA
     EYYGIPFGVL HFVPARVNGK IIPSLPSPLN RAILATVWRA HWLLAKKPED AQRRELGLPK
     ATSLSTRRIV KRGALEIQAY DELCFPGLAA EWAEYGDRRP FVGALTLELP TAADNEVLSW
     IAAGTPPIYF GFGSMPIVSP TDTVAMIAAA CADLGERALI SVKPKDLTQV PKFDHVKIVT
     SVSHAAVFPA CRAVVHHGGA GTTAASLRAG VPTLILWIFI EQPVWAAQIK RLKVGAGRRF
     SATTQRSLAA DLRTILAPQY ATRAREVANR MSKPDESVNA AADLLEDKAS RNKSRTRYQD
     C