Y2349_CORGL
ID Y2349_CORGL Reviewed; 274 AA.
AC Q8NN60;
DT 28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=DegV domain-containing protein Cgl2349/cg2579;
GN OrderedLocusNames=Cgl2349, cg2579;
OS Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS JCM 1318 / LMG 3730 / NCIMB 10025).
OC Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC Corynebacterium.
OX NCBI_TaxID=196627;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC 10025;
RX PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA Ikeda M., Nakagawa S.;
RT "The Corynebacterium glutamicum genome: features and impacts on
RT biotechnological processes.";
RL Appl. Microbiol. Biotechnol. 62:99-109(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC 10025;
RX PubMed=12948626; DOI=10.1016/s0168-1656(03)00154-8;
RA Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A.,
RA Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A.,
RA Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F.,
RA Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O.,
RA Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
RT "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its
RT impact on the production of L-aspartate-derived amino acids and vitamins.";
RL J. Biotechnol. 104:5-25(2003).
RN [3] {ECO:0007744|PDB:3EGL}
RP X-RAY CRYSTALLOGRAPHY (2.41 ANGSTROMS) IN COMPLEX WITH PALMITATE, FUNCTION,
RP AND SUBUNIT.
RG Midwest center for structural genomics (MCSG);
RT "Crystal structure of DegV family protein Cg2579 from Corynebacterium
RT glutamicum.";
RL Submitted (SEP-2008) to the PDB data bank.
CC -!- FUNCTION: Binds long-chain fatty acids, such as palmitate, and may play
CC a role in lipid transport or fatty acid metabolism.
CC {ECO:0000269|Ref.3}.
CC -!- SUBUNIT: Monomer. {ECO:0000305|Ref.3}.
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DR EMBL; BA000036; BAB99742.1; -; Genomic_DNA.
DR EMBL; BX927155; CAF21014.1; -; Genomic_DNA.
DR RefSeq; NP_601550.1; NC_003450.3.
DR RefSeq; WP_011015060.1; NC_006958.1.
DR PDB; 3EGL; X-ray; 2.41 A; A/B/C=1-274.
DR PDBsum; 3EGL; -.
DR AlphaFoldDB; Q8NN60; -.
DR SMR; Q8NN60; -.
DR STRING; 196627.cg2579; -.
DR KEGG; cgb:cg2579; -.
DR KEGG; cgl:Cgl2349; -.
DR PATRIC; fig|196627.13.peg.2285; -.
DR eggNOG; COG1307; Bacteria.
DR HOGENOM; CLU_048251_0_0_11; -.
DR OMA; MALGFCA; -.
DR EvolutionaryTrace; Q8NN60; -.
DR Proteomes; UP000000582; Chromosome.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1180.10; -; 1.
DR InterPro; IPR003797; DegV.
DR InterPro; IPR043168; DegV_C.
DR Pfam; PF02645; DegV; 1.
DR TIGRFAMs; TIGR00762; DegV; 1.
DR PROSITE; PS51482; DEGV; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Lipid-binding; Reference proteome.
FT CHAIN 1..274
FT /note="DegV domain-containing protein Cgl2349/cg2579"
FT /id="PRO_0000209761"
FT DOMAIN 3..259
FT /note="DegV"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT BINDING 39
FT /ligand="hexadecanoate"
FT /ligand_id="ChEBI:CHEBI:7896"
FT /evidence="ECO:0007744|PDB:3EGL"
FT BINDING 73
FT /ligand="hexadecanoate"
FT /ligand_id="ChEBI:CHEBI:7896"
FT /evidence="ECO:0007744|PDB:3EGL"
FT STRAND 4..8
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 9..11
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 15..20
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 23..26
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 29..32
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 37..40
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 44..57
FT /evidence="ECO:0007829|PDB:3EGL"
FT TURN 58..60
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 63..66
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 75..83
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 90..94
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 101..114
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 120..131
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 134..139
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 144..147
FT /evidence="ECO:0007829|PDB:3EGL"
FT TURN 154..156
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 160..163
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 168..172
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 175..180
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 193..200
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 206..213
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 215..218
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 221..228
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 234..239
FT /evidence="ECO:0007829|PDB:3EGL"
FT HELIX 242..248
FT /evidence="ECO:0007829|PDB:3EGL"
FT STRAND 252..258
FT /evidence="ECO:0007829|PDB:3EGL"
SQ SEQUENCE 274 AA; 28974 MW; CD918E893304E9F9 CRC64;
MPVRVIVDSS ACLPTHVAED LDITVINLHV MNNGEERSTS GLSSLELAAS YARQLERGGD
DGVLALHISK ELSSTWSAAV TAAAVFDDDS VRVVDTSSLG MAVGAAAMAA ARMAKDGASL
QECYDIAVDT LKRSETWIYL HRIDEIWKSG RISTATAMVS TALATRPIMR FNGGRMEIAA
KTRTQSKAFA KLVELAQIRA DGEPVFIAIG QNEAREAAKQ LEELLRNALP EGSSFMSVDI
DPTLAVHSGP GAVSVSAVFA NQAPELSTGK AGAK
