Y2369_ARATH
ID Y2369_ARATH Reviewed; 544 AA.
AC Q9SKH2; Q7FM55; Q8LDX9; Q9FUB3;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=BTB/POZ domain-containing protein At2g13690;
DE AltName: Full=Protein PRL1-interacting factor G;
GN Name=PRL1-IFG; OrderedLocusNames=At2g13690; ORFNames=F13J11, T10F5.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 322-544.
RX PubMed=9765207; DOI=10.1101/gad.12.19.3059;
RA Nemeth K., Salchert K., Putnoky P., Bhalerao R., Koncz-Kalman Z.,
RA Stankovic-Stangeland B., Bako L., Mathur J., Oekresz L., Stabel S.,
RA Geigenberger P., Stitt M., Redei G.P., Schell J., Koncz C.;
RT "Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD
RT protein, in Arabidopsis.";
RL Genes Dev. 12:3059-3073(1998).
RN [7]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM62951.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC006436; AAD28312.2; -; Genomic_DNA.
DR EMBL; AC007063; AAM15372.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06255.1; -; Genomic_DNA.
DR EMBL; AK117606; BAC42262.2; -; mRNA.
DR EMBL; BT029302; ABK32116.1; -; mRNA.
DR EMBL; AY085733; AAM62951.1; ALT_INIT; mRNA.
DR EMBL; AF315734; AAG31650.1; -; mRNA.
DR PIR; H84509; H84509.
DR RefSeq; NP_565358.1; NM_126948.2.
DR AlphaFoldDB; Q9SKH2; -.
DR STRING; 3702.AT2G13690.1; -.
DR iPTMnet; Q9SKH2; -.
DR PaxDb; Q9SKH2; -.
DR PRIDE; Q9SKH2; -.
DR ProteomicsDB; 242364; -.
DR EnsemblPlants; AT2G13690.1; AT2G13690.1; AT2G13690.
DR GeneID; 815853; -.
DR Gramene; AT2G13690.1; AT2G13690.1; AT2G13690.
DR KEGG; ath:AT2G13690; -.
DR Araport; AT2G13690; -.
DR TAIR; locus:2040466; AT2G13690.
DR eggNOG; ENOG502QV9R; Eukaryota.
DR HOGENOM; CLU_025834_0_1_1; -.
DR InParanoid; Q9SKH2; -.
DR OMA; IMIDREI; -.
DR OrthoDB; 809799at2759; -.
DR PhylomeDB; Q9SKH2; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9SKH2; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SKH2; baseline and differential.
DR Genevisible; Q9SKH2; AT.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR InterPro; IPR038920; BTB/POZ_dom_prot.
DR PANTHER; PTHR31060; PTHR31060; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..544
FT /note="BTB/POZ domain-containing protein At2g13690"
FT /id="PRO_0000408528"
FT DOMAIN 142..225
FT /note="BTB"
FT REGION 34..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 38
FT /note="T -> A (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 96
FT /note="V -> F (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 102..103
FT /note="TE -> AD (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 126
FT /note="F -> Y (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 163
FT /note="L -> S (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 183
FT /note="C -> CS (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 206
FT /note="L -> R (in Ref. 3; BAC42262)"
FT /evidence="ECO:0000305"
FT CONFLICT 229
FT /note="T -> K (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 243
FT /note="A -> T (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 283
FT /note="D -> A (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 300
FT /note="L -> S (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 375
FT /note="K -> N (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 461
FT /note="A -> V (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 500
FT /note="E -> Q (in Ref. 5; AAM62951)"
FT /evidence="ECO:0000305"
FT CONFLICT 513
FT /note="S -> P (in Ref. 6; AAG31650)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 544 AA; 61386 MW; DA57935E86D9E8EE CRC64;
MTMGDSDLRK PTNFGTGHLS RRRSWCCSFA VPPASPDTRS ISSRNHIPAK SQQQRPKLVP
CSPQSSKSAL NIVNRIDPRR ILSPGRVSPI DSDPTVTTMQ ETETTQEEED DAVVVDSTPN
LRSESFRAPK IEVTGSGLSE GYDARLSLKG RNGGGVLVLE LSLEVLAANS DVFSGLIAEE
KKCSSSSSSL GLKNTCRIEV CDVENLGVFR ETVELMFEES NVIIKKFMTM GVYRAIDVLE
VAAGIKFSRA VLSCLKYLEA VPWTEDEEEK LRRLLGIYSF DDDAVSEILA RFNSNETENL
QDSLSKKLVW SITSCSDVNP RNELKSLVKG LLCKSSVYEK EQPEINKEDI YRAGKCCVDS
LAKLFEEGSS SSSSKKEKPL IESISREVEN INWLLEIMID REIAEEFVEI WGKQRRLVEM
HERVSPMVRY EVSRVTGAIF IAMGKRRVQC GGEARAGLVE AWFKPMLVDF GWLQRCKKGL
DMREVEEGMG QTLLTLPVKE QYQVFMEWFR WFSKHGTECP NLSKAFQIWW RRSFLRGVES
STCR
