ID   Y2374_STAAS             Reviewed;         273 AA.
AC   Q6G6I7;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 2.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Uncharacterized protein SAS2374;
GN   OrderedLocusNames=SAS2374;
OS   Staphylococcus aureus (strain MSSA476).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282459;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSSA476;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the staphylococcal tandem lipoprotein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG44188.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BX571857; CAG44188.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000972284.1; NC_002953.3.
DR   AlphaFoldDB; Q6G6I7; -.
DR   SMR; Q6G6I7; -.
DR   KEGG; sas:SAS2374; -.
DR   HOGENOM; CLU_071589_0_0_9; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.50.20.40; -; 1.
DR   InterPro; IPR007595; Csa.
DR   InterPro; IPR038641; Csa_sf.
DR   Pfam; PF04507; DUF576; 1.
DR   TIGRFAMs; TIGR01742; SA_tandem_lipo; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..273
FT                   /note="Uncharacterized protein SAS2374"
FT                   /id="PRO_0000282164"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   273 AA;  31699 MW;  4B8E12BF768CE9D5 CRC64;
     MMHSKKLTLG ICLVLLIILI VGYVIMTKAN GQNAQIKDTF NQTLKLYPTK NLDDFYDKEG
     FRDQEFKKGD KGTWIVNSGM NIQLKGGALK SREMVLYINR NTRTTKGYFI VGEITKDKKG
     YTHDKDKKGY THDKDKKYPV KMEHNKIIPT KPIKDEKLKK EIENFKFFVQ YGNFKDFKDY
     KNGDISYNPN VPSYSAKYQL SNDDYNIQQL RKRYDIPTKK APELLLKGDG DLKGSSIGSK
     DLEFTFVQNK RENIYFTDSV EFTPSEDTSY ESN