Y2399_ARCFU
ID Y2399_ARCFU Reviewed; 224 AA.
AC O30272;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Uncharacterized tRNA/rRNA methyltransferase AF_2399;
DE EC=2.1.1.-;
GN OrderedLocusNames=AF_2399;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family. {ECO:0000305}.
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DR EMBL; AE000782; AAB91264.1; -; Genomic_DNA.
DR PIR; H69549; H69549.
DR RefSeq; WP_010879886.1; NC_000917.1.
DR AlphaFoldDB; O30272; -.
DR SMR; O30272; -.
DR STRING; 224325.AF_2399; -.
DR EnsemblBacteria; AAB91264; AAB91264; AF_2399.
DR GeneID; 24796123; -.
DR KEGG; afu:AF_2399; -.
DR eggNOG; arCOG01018; Archaea.
DR HOGENOM; CLU_021322_0_1_2; -.
DR OMA; GASQYVK; -.
DR OrthoDB; 87809at2157; -.
DR PhylomeDB; O30272; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR46429; PTHR46429; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR SUPFAM; SSF75217; SSF75217; 1.
DR TIGRFAMs; TIGR00186; rRNA_methyl_3; 1.
PE 3: Inferred from homology;
KW Methyltransferase; Reference proteome; Transferase.
FT CHAIN 1..224
FT /note="Uncharacterized tRNA/rRNA methyltransferase AF_2399"
FT /id="PRO_0000159842"
FT BINDING 177
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
FT BINDING 197
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
FT BINDING 206
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
SQ SEQUENCE 224 AA; 24289 MW; 3CD71C298EF67F23 CRC64;
MRLTDVNSIK EALLEGKVVR IYHSGERNPK ISEILEIARK KGVPIYRKDG ERFSAEVSPI
KYADFEFIVK KALTGGSFIL FLDNVVDQRN IGACIRTAEF FGAAGVVLPK RRVGSIQEGA
VKASAGAVFH IPIARVENFA SAIKKLKKLG FTTLAADLDG EDLEAVSLLL PAAVVIGGED
RGVSRPVKKQ CDFVVKIPGV GKVNSLNLSV AAGIFLYTLS RQKY
