ID   Y2403_STAAW             Reviewed;         231 AA.
AC   Q8NUV9;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Uncharacterized oxidoreductase MW2403;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=MW2403;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MW2;
RX   PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA   Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-acquired
RT   MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; BA000033; BAB96268.1; -; Genomic_DNA.
DR   RefSeq; WP_000217458.1; NC_003923.1.
DR   AlphaFoldDB; Q8NUV9; -.
DR   SMR; Q8NUV9; -.
DR   EnsemblBacteria; BAB96268; BAB96268; BAB96268.
DR   KEGG; sam:MW2403; -.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; ITGGRNW; -.
DR   Proteomes; UP000000418; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..231
FT                   /note="Uncharacterized oxidoreductase MW2403"
FT                   /id="PRO_0000300474"
FT   ACT_SITE        153
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         140
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   231 AA;  24577 MW;  BDA4ACD8D903F40F CRC64;
     MTVLTDKIAV VTGAGSGIGE AIATLLHEEG AKVVLAGRNK EKLQNVANQL SQDSVKVVPT
     DVTNKEEVDE LIKIAQQTFG GLDIVINSAG QMLSSKITDY QVDEWDSMID VNIKGTLYTV
     QAALPTMLEQ SSGHLINIAS ISGFEVTKSS TIYSATKAAV HTITQGLEKE LAKTGVKVTS
     ISPGMVDTAI TAAYNPSDRK KLDPQDIAEA VLYALTQPSH VNVNEITVRP V