Y2424_ARATH
ID Y2424_ARATH Reviewed; 441 AA.
AC Q9ZUH1;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=BTB/POZ domain-containing protein At2g24240;
GN OrderedLocusNames=At2g24240; ORFNames=F27D4.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
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DR EMBL; AC005967; AAD03385.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07547.1; -; Genomic_DNA.
DR EMBL; BT020254; AAV84475.1; -; mRNA.
DR EMBL; BT020435; AAW30014.1; -; mRNA.
DR EMBL; AK229200; BAF01070.1; -; mRNA.
DR PIR; C84634; C84634.
DR RefSeq; NP_180001.1; NM_127985.4.
DR AlphaFoldDB; Q9ZUH1; -.
DR STRING; 3702.AT2G24240.1; -.
DR PaxDb; Q9ZUH1; -.
DR PRIDE; Q9ZUH1; -.
DR ProteomicsDB; 242844; -.
DR EnsemblPlants; AT2G24240.1; AT2G24240.1; AT2G24240.
DR GeneID; 816958; -.
DR Gramene; AT2G24240.1; AT2G24240.1; AT2G24240.
DR KEGG; ath:AT2G24240; -.
DR Araport; AT2G24240; -.
DR TAIR; locus:2047540; AT2G24240.
DR eggNOG; KOG2714; Eukaryota.
DR HOGENOM; CLU_045194_1_0_1; -.
DR InParanoid; Q9ZUH1; -.
DR OMA; YEIFASC; -.
DR OrthoDB; 530305at2759; -.
DR PhylomeDB; Q9ZUH1; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9ZUH1; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZUH1; baseline and differential.
DR Genevisible; Q9ZUH1; AT.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.130.10.10; -; 1.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF50978; SSF50978; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..441
FT /note="BTB/POZ domain-containing protein At2g24240"
FT /id="PRO_0000405329"
FT DOMAIN 6..76
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ SEQUENCE 441 AA; 49167 MW; BD87ED5A8CC6B8A6 CRC64;
MGISKDRIKF NVGGRLFETT ATTLANAGRD SFFGALFDDE WNLSPLEDSI LFVDRNSDCF
AVLLDLLRTG DLNVPANIPE RLLHREASFY GLLDHVRTAK WGPFDGNRLR LSDSVKGIAP
GDGTAIRAGP DGGCCVAHGS VVHVFDWMLE EHSPINLDYQ RVNDVGWIDS DNIVLSACEK
LGRGDGGMGL FSSSSGDLRY KFQVCHENQV KSYTAGALSF SPDYEIFASC KGRSNEYGIG
VWDQITGKQT DFFYESPGWS LGDADKLQWL NGKNCLLVAT LFPRKDNCYI SLLDFRDKNM
VWSWSDIGSP MAIDEKRVRD AIAMEDSNSI CVVNEFEDLG FIDLRMYGGS VRWSSRSKLM
KSKMPDEPCY PKLALHEGQL FSSMNDSISV FCGPDWVLTS RLRRSYGGSI CDFSIGGDRL
FALHSEENVF DVWETPPCPI I
