ID   Y243_ARCFU              Reviewed;         529 AA.
AC   O29996;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Uncharacterized protein AF_0243;
GN   OrderedLocusNames=AF_0243;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU01266};
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DR   EMBL; AE000782; AAB90990.1; -; Genomic_DNA.
DR   PIR; C69280; C69280.
DR   RefSeq; WP_010877754.1; NC_000917.1.
DR   AlphaFoldDB; O29996; -.
DR   STRING; 224325.AF_0243; -.
DR   EnsemblBacteria; AAB90990; AAB90990; AF_0243.
DR   GeneID; 24793775; -.
DR   KEGG; afu:AF_0243; -.
DR   eggNOG; arCOG01359; Archaea.
DR   HOGENOM; CLU_533842_0_0_2; -.
DR   OMA; HTPGKYL; -.
DR   OrthoDB; 19362at2157; -.
DR   PhylomeDB; O29996; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.30.20; -; 1.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SMART; SM00729; Elp3; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..529
FT                   /note="Uncharacterized protein AF_0243"
FT                   /id="PRO_0000106767"
FT   DOMAIN          157..410
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         171
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         176
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         179
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
SQ   SEQUENCE   529 AA;  60503 MW;  57E9FBC20D284BBF CRC64;
     MKAAIIDGYV DEPSCLGVPP YVAPYPRYIY GMLKSLDYEA TYFTIDHLRA HPETVERLKK
     FDLAVIIAGI AVPGKYLGGK PLSKKELFSM GLAERNLLVG PITLELSQKE LRMLEDVEIE
     VIDFPFERKL FERLGGEKFN LNAFAARGAE VVRQHPDFPH IICEIETYRG CYWGKCSFCI
     ERVHSLWFRS PEDVLGEVKA LYDCGVRHFR LGRQTDFFSY LGEFEGVPRP NPEAMKKFHR
     AIWDLCPKIK TLHIDNVNPK TIAEHPEESA ELIKTIVMYQ TPGNVAAMGL ESADERVVRK
     NSLAASPEEV MFAIELINRY GRHPSYNGLP YFLPGINFVI GLKGETKETF ELNYRFLEEV
     MERNLLLRRI NIRQVKIFPG TPMEKEGDRR LKKHRKEFIA FKNRVRENID TPMLKKILPK
     GRRITDLRVE VEGKISYARQ LATYPILVGL VGKYPRNLYV DARVVDYGHR SVTAVEADLD
     VNKATLEQLE FLLGKVGREV YMRRPIGSDA ELEAIGGKEA LVYLKVGGE