Y2443_STAAW
ID Y2443_STAAW Reviewed; 223 AA.
AC Q79ZZ6;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Putative NAD(P)H nitroreductase MW2443;
DE EC=1.-.-.-;
GN OrderedLocusNames=MW2443;
OS Staphylococcus aureus (strain MW2).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=196620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MW2;
RX PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT "Genome and virulence determinants of high virulence community-acquired
RT MRSA.";
RL Lancet 359:1819-1827(2002).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000305};
CC -!- SIMILARITY: Belongs to the nitroreductase family. {ECO:0000305}.
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DR EMBL; BA000033; BAB96308.1; -; Genomic_DNA.
DR RefSeq; WP_000069098.1; NC_003923.1.
DR AlphaFoldDB; Q79ZZ6; -.
DR SMR; Q79ZZ6; -.
DR EnsemblBacteria; BAB96308; BAB96308; BAB96308.
DR KEGG; sam:MW2443; -.
DR HOGENOM; CLU_070764_4_1_9; -.
DR OMA; PWHFVVA; -.
DR Proteomes; UP000000418; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02149; NfsB-like; 1.
DR Gene3D; 3.40.109.10; -; 1.
DR InterPro; IPR033878; NfsB-like.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR Pfam; PF00881; Nitroreductase; 1.
DR SUPFAM; SSF55469; SSF55469; 1.
PE 3: Inferred from homology;
KW Flavoprotein; FMN; NAD; NADP; Oxidoreductase.
FT CHAIN 1..223
FT /note="Putative NAD(P)H nitroreductase MW2443"
FT /id="PRO_0000277535"
SQ SEQUENCE 223 AA; 25375 MW; 86CFC18027E2FCB6 CRC64;
MSNMNQTIMD AFHFRHATKQ FDPQKKVSKE DFETILESGR LSPSSLGLEP WKFVVIQDQA
LRDELKAHSW GAAKQLDTAS HFVLIFARKN VTSRSPYVQH MLRDIKKYEA QTIPAVEQKF
DAFQADFHIS DNDQALYDWS SKQTYIALGN MMTTAALLGI DSCPMEGFSL DTVTDILANK
GILDTEQFGL SVMVAFGYRQ QDPPKNKTRQ AYEDVIEWVG PKE