ID   Y2445_STAEQ             Reviewed;         261 AA.
AC   Q5HKA4;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Uncharacterized lipoprotein SERP2445;
DE   Flags: Precursor;
GN   OrderedLocusNames=SERP2445;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the staphylococcal tandem lipoprotein family.
CC       {ECO:0000305}.
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DR   EMBL; CP000029; AAW53308.1; -; Genomic_DNA.
DR   RefSeq; WP_010959361.1; NC_002976.3.
DR   AlphaFoldDB; Q5HKA4; -.
DR   SMR; Q5HKA4; -.
DR   STRING; 176279.SERP2445; -.
DR   EnsemblBacteria; AAW53308; AAW53308; SERP2445.
DR   KEGG; ser:SERP2445; -.
DR   eggNOG; ENOG5033UD8; Bacteria.
DR   HOGENOM; CLU_071589_0_1_9; -.
DR   OMA; NINRNTR; -.
DR   OrthoDB; 1153550at2; -.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.50.20.40; -; 1.
DR   InterPro; IPR007595; Csa.
DR   InterPro; IPR038641; Csa_sf.
DR   Pfam; PF04507; DUF576; 1.
DR   TIGRFAMs; TIGR01742; SA_tandem_lipo; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..261
FT                   /note="Uncharacterized lipoprotein SERP2445"
FT                   /id="PRO_0000282186"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   261 AA;  30541 MW;  695782E9F6C9250F CRC64;
     MKHSKKLLLC ISFLLITFFI GGCGFMNKDD GKETEIKQNF NKMLNVYPTK NLENFYDKEG
     YRDEEFDKDD KGTWIVHSKM VIEPKGKNME SRGMVLFINR NTRTSKGYFI VNEIEKDRKG
     RPINNKKKYP VKMKNNKIIP TKPISNDKLK KEIENFKFFV QYGNFKDIKN YKDGDISYNP
     NVPSYSAKYQ LSNNEYNVQQ LRKRYDIPTK KVPKLLLKGD GDLKGSSVGS KNLEFTFIEN
     KEENIYFTDS VLFSPSEDNE S