ID   Y2450_AERHH             Reviewed;         561 AA.
AC   A0KL13;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Putative transport protein AHA_2450 {ECO:0000255|HAMAP-Rule:MF_01015};
GN   OrderedLocusNames=AHA_2450;
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS   13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC
RC   2358 / NCIMB 9240 / NCTC 8049;
RX   PubMed=16980456; DOI=10.1128/jb.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H.,
RA   Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA   Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01015};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01015}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family. YbjL
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01015}.
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DR   EMBL; CP000462; ABK38935.1; -; Genomic_DNA.
DR   RefSeq; WP_011706282.1; NC_008570.1.
DR   RefSeq; YP_856964.1; NC_008570.1.
DR   AlphaFoldDB; A0KL13; -.
DR   STRING; 380703.AHA_2450; -.
DR   EnsemblBacteria; ABK38935; ABK38935; AHA_2450.
DR   GeneID; 64358464; -.
DR   KEGG; aha:AHA_2450; -.
DR   PATRIC; fig|380703.7.peg.2448; -.
DR   eggNOG; COG0569; Bacteria.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_2_2_6; -.
DR   OMA; RDGKNYF; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 1.
DR   HAMAP; MF_01015; YbjL; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR023017; Transp_YbjL_put.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 2.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..561
FT                   /note="Putative transport protein AHA_2450"
FT                   /id="PRO_0000329136"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        409..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        450..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        476..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   TRANSMEM        541..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   DOMAIN          206..291
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
FT   DOMAIN          293..376
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01015"
SQ   SEQUENCE   561 AA;  60520 MW;  39B0BCEAF81400B6 CRC64;
     MTIDFVTLLH QSDSLLLFVV LAFGLLLGKV RFGNFQIGNT IGVLFTALLF GQMGFEFTAT
     TENVGFMLFI FCVGIEAGPH FFSVFLRDGI HYITLTLVIL LTALFLTVGL AKFFNLGPGM
     AAGILAGSLT STPALVGAQD ALRSGLLNLP HQTDMQSVLD NMGIGYALTY LVGLVGLMLV
     VRYLPSLARL DLNTEAQKIA RERGLSDNES RKTYLPIIRA YRVGPELAAW IGGRTLRETG
     IYPHTGCYVE RIRRNGILAS PDGDAVIQEG DEIALVGYPE SHEKLDVNYR NGKEVFDRNL
     LDLQIVTEEI VVKNDAVVGR HLVELNLTEK GCFLNRVVRS QIEMPFDRNI MLQKGDVLQI
     SGEKQRVKLL ANKIGFISIH SQTTDLVAFT TFFVLGLLIG SVSLVFGQLE FGLGNAVGLL
     LAGILMGYLR ANHPTVGYVP PGALRLAKDL GLAVFMVSTG LKAGGGILDH LSQVGAVVLF
     SGMLVTTLPV LVGYLFGVWV LKMNPALLLG AITGARTCAP AMDVVNEAAN SSIPALGYAG
     TYAVANVMLT LAGSFIIGFW F