ID   Y2452_STAAB             Reviewed;         185 AA.
AC   Q2YWD0;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=HTH-type transcriptional regulator SAB2452;
GN   OrderedLocusNames=SAB2452;
OS   Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bovine RF122 / ET3-1;
RX   PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA   Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT   "Molecular correlates of host specialization in Staphylococcus aureus.";
RL   PLoS ONE 2:E1120-E1120(2007).
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DR   EMBL; AJ938182; CAI82140.1; -; Genomic_DNA.
DR   RefSeq; WP_001224177.1; NC_007622.1.
DR   AlphaFoldDB; Q2YWD0; -.
DR   SMR; Q2YWD0; -.
DR   KEGG; sab:SAB2452; -.
DR   HOGENOM; CLU_069356_17_2_9; -.
DR   OMA; DAIENRQ; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..185
FT                   /note="HTH-type transcriptional regulator SAB2452"
FT                   /id="PRO_0000286689"
FT   DOMAIN          6..66
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DNA_BIND        29..48
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   185 AA;  22315 MW;  C4E8F3937203711E CRC64;
     MRKDAIENRQ RIEEIAHKLF DEEGVENISM NRIAKELGIG MGTLYRHFKD KSDLCFYVIQ
     RDLNTFITQF KQIKDDYHSD YEVMKVSLDY LLQFKIDNKT LLHCIEAGNN KLRFYQSAFY
     QELFDFYYDL FKSDDDIFTK FKTDMLLQSL STSVFAFQIE HRHISIEAYR NYLLNIYLDE
     VERND