ID   Y2453_MYCLE             Reviewed;          87 AA.
AC   Q9CB43;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   14-AUG-2001, sequence version 2.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Uncharacterized protein ML2453;
DE   Flags: Precursor;
GN   OrderedLocusNames=ML2453;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv0476. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAC31970.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL583925; CAC31970.1; ALT_INIT; Genomic_DNA.
DR   PIR; B87216; B87216.
DR   RefSeq; WP_010908910.1; NC_002677.1.
DR   AlphaFoldDB; Q9CB43; -.
DR   STRING; 272631.ML2453; -.
DR   EnsemblBacteria; CAC31970; CAC31970; CAC31970.
DR   KEGG; mle:ML2453; -.
DR   Leproma; ML2453; -.
DR   eggNOG; ENOG5033BDI; Bacteria.
DR   HOGENOM; CLU_135072_2_1_11; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR019662; DUF2516.
DR   Pfam; PF10724; DUF2516; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..87
FT                   /note="Uncharacterized protein ML2453"
FT                   /id="PRO_0000014073"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   87 AA;  9179 MW;  F83FA8FEA95A511E CRC64;
     MLVLQLAVLV TAVYAFVHAA LQRPDAYTAA EKLTKPVWLV ILGAAVSLTS ILGFVFGVLG
     IVIAACAAGV YLVDVRPKLL DIQGKSR