ID   Y2453_STAEQ             Reviewed;         259 AA.
AC   Q5HK97;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Uncharacterized lipoprotein SERP2453;
DE   Flags: Precursor;
GN   OrderedLocusNames=SERP2453;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the staphylococcal tandem lipoprotein family.
CC       {ECO:0000305}.
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DR   EMBL; CP000029; AAW53322.1; -; Genomic_DNA.
DR   RefSeq; WP_010959364.1; NC_002976.3.
DR   AlphaFoldDB; Q5HK97; -.
DR   SMR; Q5HK97; -.
DR   STRING; 176279.SERP2453; -.
DR   EnsemblBacteria; AAW53322; AAW53322; SERP2453.
DR   KEGG; ser:SERP2453; -.
DR   eggNOG; ENOG5033UD8; Bacteria.
DR   HOGENOM; CLU_071589_0_0_9; -.
DR   OMA; WILYSEM; -.
DR   OrthoDB; 1153550at2; -.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.50.20.40; -; 1.
DR   InterPro; IPR007595; Csa.
DR   InterPro; IPR038641; Csa_sf.
DR   Pfam; PF04507; DUF576; 1.
DR   TIGRFAMs; TIGR01742; SA_tandem_lipo; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..259
FT                   /note="Uncharacterized lipoprotein SERP2453"
FT                   /id="PRO_0000282189"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   259 AA;  29914 MW;  EE661F8DFF4515B8 CRC64;
     MKHSKKLLLC ISFLLITVFI SGCGSMTKED NKEEKIKKGF EKTLGMYPIK NLEDLYDKEG
     YRDEEFDEGD KGTWILYSEM VIQRKGDDLV TRGMILKVNR NTRTSKGNYI INKISTDSKG
     VSRNTQKKFP VKMENNKIIP IKKIEDSKIK REIDEFKFFA QYANFNSLKD YKNGDIATNP
     KVPSYSAEYD LENSDYNVKQ LRKRYDIPTQ QAPKLLLKGT GDLKGSSIGS KDIEFTFIEK
     PKKNIYFSDS LDYKPSEGH