ID   Y2462_STAA3             Reviewed;         223 AA.
AC   Q2FDY2;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Putative NAD(P)H nitroreductase SAUSA300_2462;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SAUSA300_2462;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the nitroreductase family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD22119.1; -; Genomic_DNA.
DR   RefSeq; WP_000069101.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FDY2; -.
DR   SMR; Q2FDY2; -.
DR   EnsemblBacteria; ABD22119; ABD22119; SAUSA300_2462.
DR   KEGG; saa:SAUSA300_2462; -.
DR   HOGENOM; CLU_070764_4_1_9; -.
DR   OMA; PWHFVVA; -.
DR   Proteomes; UP000001939; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02149; NfsB-like; 1.
DR   Gene3D; 3.40.109.10; -; 1.
DR   InterPro; IPR033878; NfsB-like.
DR   InterPro; IPR029479; Nitroreductase.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   Pfam; PF00881; Nitroreductase; 1.
DR   SUPFAM; SSF55469; SSF55469; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NAD; NADP; Oxidoreductase.
FT   CHAIN           1..223
FT                   /note="Putative NAD(P)H nitroreductase SAUSA300_2462"
FT                   /id="PRO_0000277538"
SQ   SEQUENCE   223 AA;  25389 MW;  86CFC18027E327C6 CRC64;
     MSNMNQTIMD AFHFRHATKQ FDPQKKVSKE DFETILESGR LSPSSLGLEP WKFVVIQDQA
     LRDELKAHSW GAAKQLDTAS HFVLIFARKN VTSRSPYVQH MLRDIKKYEA QTIPAVEQKF
     DAFQADFHIS DNDQALYDWS SKQTYIALGN MMTTAALLGI DSCPMEGFSL DTVTDILANK
     GILDTEQFGL SVMVAFGYRQ QEPPKNKTRQ AYEDVIEWVG PKE