ID   Y2465_YERPN             Reviewed;         135 AA.
AC   Q1CGT7; C4GVE7;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=UPF0299 membrane protein YPN_2465 {ECO:0000255|HAMAP-Rule:MF_01144};
GN   OrderedLocusNames=YPN_2465; ORFNames=YP516_2778;
OS   Yersinia pestis bv. Antiqua (strain Nepal516).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=377628;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RA   Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L.,
RA   Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R.,
RA   Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.;
RT   "Yersinia pestis Nepal516A whole genome shotgun sequencing project.";
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01144}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01144}.
CC   -!- SIMILARITY: Belongs to the UPF0299 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01144}.
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DR   EMBL; CP000305; ABG18793.1; -; Genomic_DNA.
DR   EMBL; ACNQ01000014; EEO76031.1; -; Genomic_DNA.
DR   RefSeq; WP_002211971.1; NZ_ACNQ01000014.1.
DR   AlphaFoldDB; Q1CGT7; -.
DR   SMR; Q1CGT7; -.
DR   EnsemblBacteria; ABG18793; ABG18793; YPN_2465.
DR   GeneID; 66842038; -.
DR   KEGG; ypn:YPN_2465; -.
DR   HOGENOM; CLU_113736_1_1_6; -.
DR   OMA; MLQTFAI; -.
DR   Proteomes; UP000008936; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01144; UPF0299; 1.
DR   InterPro; IPR005538; LrgA/CidA.
DR   InterPro; IPR022957; Uncharacterised_UPF0299.
DR   PANTHER; PTHR33931; PTHR33931; 1.
DR   Pfam; PF03788; LrgA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..135
FT                   /note="UPF0299 membrane protein YPN_2465"
FT                   /id="PRO_1000085045"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01144"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01144"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01144"
SQ   SEQUENCE   135 AA;  15294 MW;  81315E1CF9069FF5 CRC64;
     MRNMMSLCWQ YLRAFTIIYL CLWAGKALAL LLPIVIPGSI IGMLILFVLL TLQILPSPWV
     KPSCQLLIRY MALLFVPIGV GVMQYYEQLT KQFGPIVVSC FISTLIVMLV VAYSSHYVHR
     DRKVISPSTP TEGEK