ID   Y246_MESH2              Reviewed;         484 AA.
AC   P0C0K2; P46188; Q601F6;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Uncharacterized protein mhp246;
GN   OrderedLocusNames=mhp246;
OS   Mesomycoplasma hyopneumoniae (strain 232) (Mycoplasma hyopneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mesomycoplasma.
OX   NCBI_TaxID=295358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=232;
RX   PubMed=15489423; DOI=10.1128/jb.186.21.7123-7133.2004;
RA   Minion F.C., Lefkowitz E.J., Madsen M.L., Cleary B.J., Swartzell S.M.,
RA   Mahairas G.G.;
RT   "The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of
RT   swine mycoplasmosis.";
RL   J. Bacteriol. 186:7123-7133(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE017332; AAV27787.1; -; Genomic_DNA.
DR   RefSeq; WP_011206083.1; NC_006360.1.
DR   AlphaFoldDB; P0C0K2; -.
DR   STRING; 295358.mhp246; -.
DR   TCDB; 2.A.1.76.1; the major facilitator superfamily (mfs).
DR   EnsemblBacteria; AAV27787; AAV27787; mhp246.
DR   KEGG; mhy:mhp246; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_033053_0_0_14; -.
DR   OMA; WGIQGVM; -.
DR   PhylomeDB; P0C0K2; -.
DR   Proteomes; UP000006822; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011699; MFS_Mycoplasma.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07672; MFS_Mycoplasma; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..484
FT                   /note="Uncharacterized protein mhp246"
FT                   /id="PRO_0000066083"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        398..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        440..460
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   484 AA;  54500 MW;  198C3F9F97DC4345 CRC64;
     MKKNFILNFA TKNVKEKKLS FGVGITLWAL IVFAYMIFVM NWGFASAGLN GKAGISGYLG
     HFFPNANEAP GTVVNQAVNW GITIGRGIGS VLVGWLIVKI SHKYTVILSL FFMLFGIIAP
     YSPTYAGFII LRTIFAIGGT MQIILIQPVV SNYLNQRQKA VISQFSPFFY PIGTIITLIP
     FAGIIGQEAQ KAFRDNWQIV FLVIGLLTLI PLIGYIILGT KFDLYPSNIE KRNKQEKLSL
     ATFFKQKDTW YWTILYGSWL VAVVFPFTFS KPIFHRLIGD SDGTFNDKIS VFLIFFLAGM
     FLGPFTIGLL SKYQLQRRKY ISTIITLGVF FYVLATVVFV LKVGKNYEYA KSYTDGWTWL
     FLFLGLFMGI CLWGIQGVML NLPHEYKGSN PYRVGFQFGL IWGLGYTAFT IATIITSLVN
     TPPGIDLKKL ELNNVDGYAL GAYILIIIFS LVSSIGLALL KEPNPEYKKL LKIRSFSEIE
     RIKK