ID   Y2476_STRGG             Reviewed;         196 AA.
AC   B1W2E1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Putative NADH dehydrogenase/NAD(P)H nitroreductase SGR_2476 {ECO:0000255|HAMAP-Rule:MF_01204};
DE            EC=1.-.-.- {ECO:0000255|HAMAP-Rule:MF_01204};
GN   OrderedLocusNames=SGR_2476;
OS   Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=455632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / NBRC 13350;
RX   PubMed=18375553; DOI=10.1128/jb.00204-08;
RA   Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA   Yamashita A., Hattori M., Horinouchi S.;
RT   "Genome sequence of the streptomycin-producing microorganism Streptomyces
RT   griseus IFO 13350.";
RL   J. Bacteriol. 190:4050-4060(2008).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01204};
CC   -!- SIMILARITY: Belongs to the nitroreductase family. HadB/RutE subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01204}.
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DR   EMBL; AP009493; BAG19305.1; -; Genomic_DNA.
DR   RefSeq; WP_012379228.1; NC_010572.1.
DR   AlphaFoldDB; B1W2E1; -.
DR   SMR; B1W2E1; -.
DR   EnsemblBacteria; BAG19305; BAG19305; SGR_2476.
DR   GeneID; 6215080; -.
DR   KEGG; sgr:SGR_2476; -.
DR   PATRIC; fig|455632.4.peg.2520; -.
DR   eggNOG; COG0778; Bacteria.
DR   HOGENOM; CLU_084441_0_0_11; -.
DR   OMA; LMVVNIG; -.
DR   OrthoDB; 1847197at2; -.
DR   Proteomes; UP000001685; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-UniRule.
DR   CDD; cd02148; RutE-like; 1.
DR   Gene3D; 3.40.109.10; -; 1.
DR   HAMAP; MF_01204; Oxidoreductase_RutE_HadB; 1.
DR   InterPro; IPR029479; Nitroreductase.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   InterPro; IPR023936; RutE-like.
DR   Pfam; PF00881; Nitroreductase; 1.
DR   SUPFAM; SSF55469; SSF55469; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NAD; NADP; Oxidoreductase.
FT   CHAIN           1..196
FT                   /note="Putative NADH dehydrogenase/NAD(P)H nitroreductase
FT                   SGR_2476"
FT                   /id="PRO_1000138702"
SQ   SEQUENCE   196 AA;  21386 MW;  308485CC04A0FFF0 CRC64;
     MSLVLDPAAQ DLLFREARTA NTFTDEPVTD EQVQAIYDLV KFGPTAFNQS PLRVVLVRSA
     EGRERLVQHM AEGNRPKTAT APLVAILAAD NEFHEELPAL LPHFPQAKDL FFSERPVRES
     AAGLNAALQA AYFIIGVRAA GLAAGPMTGY DAAGIQKEFL DDDHTPLMVV NIGKPGDDAW
     FPRSPRLSFD EVITTV